PP001 Intramedullary fixation and subsequent lengthening of A–frame free vascularised fibula grafts for recruction of the distal femur in Osteosarcoma patients
Ulrich Lenze¹, Mark O’Sullivan², Dave McCombe³, Christopher Coombs³, Leo Donnan^2
1Department of Orthopaedics, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; ²Department of Orthopaedics, The Royal Children's Hospital, Melbourne, Australia; ³Department of Plastic and Maxillofacial Surgery, The Royal Children's Hospital, Melbourne, Australia

PP002 Reconstruction with vascularized fibula and lumbar-pelvic instrumentation for the defect after plevic IV maglignant lesion resection
Jin Xiong,  Shoufeng Wang, Benlong Shi
Department of Orthopadic, Drum Tower Hospital, Nanjing University Medical School, Nanjing, China

PP003 Reconstruction of bone defect with allograft and retrograde intramedullary nail for distal tibia osteosarcoma
Benlong Shi, Shoufeng Wang, Jin Xiong
Department of Orthopadics, Drum Tower Hospital, Nanjing University Medical School, Nanjing, China

PP004 Massive biological reconstruction by combination use of clavicula pro humero and free vascularized fibula graft after huge osteosarcoma arising in proximal humerus in a child: A case report
Yoji Shido, Yukihiro Matsuyama
Dept. of Orthopedic Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan

PP005 Combined use of extracorporeally irradiated autograft and vascularized bone graft for reconstruction of massive bone and joint defects after resection of malignant musculoskeletal tumor
Atsushi Mihara¹, Keiichi Muramatsu¹, Ryuta Iwanaga¹,Koichiro Ihara², Takashi Sakai^1
1Dept. of Orthopedic Surgery, Yamaguchi University Graduate School of Medicine, Ube-City, Japan; ²Dept. of Orthopedic Surgery, Kanmon Medical Center, Shimonoseki-City, Japan

PP006 Updates on the use and clinical outcomes of bone allograft for orthopaedic oncology in the past 35 years from Bangkok Biomaterial Center
Chandhanarat Chandhanayingyong¹, Jirapa Wonglex², Rathathai Muangtham², Apichat Asavamongkolkul¹, Saranatra Waikakul¹, Rapin Phimolsarnti^1
1Department of Orthopaedic Surgery, Faculty of Medicine Siriraj Hospital, Bangkok, Thailand; ²Bangkok Biomaterial Center under the patronage of H.R.H. Princess Galyanivadhana of Thailand, Bangkok, Thailand

PP007 Extensor mechanism allograft and radiotherapy in the treatment of soft tissue sarcomas around the knee: Presentation of two clinical cases
Francisco Baixauli, José Amaya, Manuel Angulo, Carolina De La calva, Ignacio Baixauli
Hospital Universitario Y Politecnico La Fe, Valencia, Spain

PP008 Free Vascularised Fibular Graft (FVFG) augmented by cadaveric strut allograft for the management of long bone defects and long term outcomes
Konstantinos Malizos¹, Nikolaos Stefanou¹, Zoe Dailiana¹, Socratis Varitimidis¹, Panagiotis Papagelopoulos², Vasileios Kontogeorgakos^2
1Department of Orthopaedic Surgery and Musculosceletal Trauma, University of Thessaly, Faculty of Medicine, Larissa, Greece; ²First Department of Orthopaedics, National and Kapodistrian University of Athens, Faculty of Medicine, Athens, Greece

PP009 Bone preservation after revision allograft prosthetic composite reconstruction of the proximal humerus
Taylor Reif¹, Ashley Aratani¹, Andre Spiguel¹, Bradley Schoch¹, Joaquin Sanchez-Sotelo², Benjamin Wilke^3
1University of Florida, Gainesville, United States; ²Mayo Clinic, Rochester, United States; ³Mayo Clinic, Jacksonville, United States

PP010 Salvage of limb salvage in intercalary reconstruction of the lower limb with bone graft
Maurizio Scorianz¹, Francesca Totti¹, Francesco Muratori¹, Matteo Innocenti¹, Xhulio Prifti¹, Alberto Schiavo¹, Giovanni Beltrami², Rodolfo Capanna³, Domenico Andrea Campanacci^1
1Department of Orthopedic Oncology and Reconstructive Surgery, Careggi Universitary Hospital, Firenze, Italy; ²Department of Paediatric Orthopaedic Oncology, Careggi Universitary Hospital, Firenze, Italy; ³Clinic of Orthopaedics and Traumatology, University of Pisa, Pisa, Italy

PP011 Osteoarticular allograft with and without ligamentary osseous fixation. Is the extra-surgical work worth it?
Adriana Hernandez Lopez¹, Alejandro Sanchez Hernandez¹, Carlos Eduardo Cuervo Lozano^2
1Instituto de Ortopedia, Centro Medico Zambrano Hellion, Tec Salud, San Pedro Garza García, Mexico; ²Departamento de Ortopedia y Traumatología, Hospital "Dr. José Eleuterio González" Universidad Autónoma de Nuevo León, Monterrey, Mexico

PP012 Limb preservation of the upper extremity using a frozen bone allograft with vascularized fibula and latissimus dorsi flap in a IIIB  T2 proximal humerus conventional osteosarcoma: A case presentation
Patricia Bonilla¹, M. Pacheco², A. Ríos², I. Veliz^3
1Hospital del Niño Dr. José Renán Esquivel, Panama City, Panama; ²Complejo Hospitalario Metropolitano, Panama City, Panama; ³Instituto Oncológico Nacional and HOPE Center, Panama City, Panama

PP013 Distal tibia sarcoma treatment using allograft arthrodesis of the ankle
Patricia Bonilla¹, C. Lores², J. Mejia¹, J. Navia², Marina Pacheco³, E. Pedromo¹, M. Medina¹, C. Aguilar⁴, I. Veliz^4
1Hospital del Niño Dr. José Renán Esquivel, Panama City, Panama; ²Hospital Universitario del Valle, Cali, Colombia, ³Centro Hospitalario Metropolitano, Panama City, Panama, ⁴Instituto Oncológico Nacional, Panama City, Panama

PP014 Organ-preserving operations with vascular reconstruction for removing of soft tissues tumors of the extremities
Djamila Polatova, M. Sharipov, A. Suyumov, Mirza Gafur-Akhunov, Khurshid Abdikarimov, Ulugbek Islamov, Alexandr Savkin, Rasul Davletov, Bahridil Sultonov, Nizom Khudoyberdiyev
Republican Specialized Scientific-Practical Medical Centre of Oncology and Radiology, Ministry of Healthcare, Tashkent, Uzbekistan

PP015 Early outcomes of the Compress® Transdermal Implant System in transhumeral and transfemoral amputations
Jonathan Forsberg¹, Benjamin Kyle Potter^2
1Department of Orthopaedic Surgery, Johns Hopkins University, Baltimore, United States; ²Orthopaedics, USU-Walter Reed Department of Surgery, Bethesda, United States

PP016 Functional and quality of life evaluation of patients with bone tumors submitted to lower limb amputation
Silvia Wasserstein, Dan Viola, Eliana Caran, Reynaldo Jesus-Garcia
IOP / GRAACC, São Paulo, Brazil

PP017 Effect of virtual reality augmented physiotherapy for rehabilitation in 54 children following major reconstructive procedures for bone and soft tissues
Pawar Chetan¹,Sai Paavani Manohar¹, Goyal Sowmya¹, Pramod Chinder¹, Suraj Hindiskere^2
1HCG Hospital, Bangalore, India; ²The Yellow Ribbon, India

PP018 Analysis of phantom limb pain and functional outcome after lower limb amputation for musculoskeletal malignancies
Hiromori Sagae¹, Masato Sugawara², Daiichiro Takahara², Takashi Tsuchiya³, Michiaki Takagi^2
1Department οf Orthopaedic Surgery, Yamagata Prefectural Kahoku Hospital, Yamagata, Japan; ²Department of Orthopaedic Surgery, Yamagata University Faculty of Medicine, Yamagata, Japan; ³Department of Orthopaedic Surgery, Yamagata Saisei Hospital, Yamagata, Japan

PP019 Rotationplasty - Limb salvage presentation in 5 cases
Diego Sanches, Márcio Moura, Álvaro Pinto, Sibele Milano, Marcella Villela
Hospital do Trabalhador - UFPR, Curitiba, Brazil

PP020 Negative pressure wound therapy for lower limb amputation patients - A case control trial
Brendan Chan, David Shields, Helen Findlay, Ashish Mahendra, Sanjay Gupta
Glasgow Royal Infirmary, Glasgow, United Kingdom

PP021 What is the best shape of a drilled hole in treatment of bone tumor?
Tadashi Iwai, Manabu Hoshi, Naoto Oebisu, Kumi Ogi, Akiyoshi Shimatani, Naoki Takada, Hiroaki Nakamura
Department of Orthopedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan

PP022 Radiation dose deviations by titanium versus CF/PEEK implants in long bones
Christina Villefort¹, Christoph J. Laux¹, Stefanie Ehrbar², Lotte Wilke², Matthias Guckenberger², Daniel A. Müller^1
1Balgrist University Hospital, Department of Orthopaedics, Zurich, Switzerland; ²University Hospital Zurich, Department of Radiation Oncology, Zurich, Switzerland

PP023 Skeletal muscle cell oxidative stress as a possible therapeutic target for sarcopenia
Hideyuki Kinoshita, Tsukasa Yonemoto, Hiroto Kamoda, Yoko Hagiwara, Toshinori Tsukanishi, Takeshi Ishii
Chiba Cancer Center, Chiba, Japan

PP024 Glycogen synthase kinase-3β is a new therapeutic target in synovial sarcoma and fibrosarcoma
Kensaku Abe¹, Norio Yamamoto¹, Takahiro Domoto², Katsuhiro Hayashi¹, Akihko Takeuchi¹, Shinji Miwa¹, Kentaro Igarashi¹, Yu Aoki¹, Takashi Higuchi¹, Yuta Taniguchi¹, Hirotaka Yonezawa¹, Yoshihiro Araki¹, Sei Morinaga¹, Toshinari Minamoto², Hiroyuki Tsuchiya^1
1Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa; Japan, ²Division of Translational and Clinical Oncology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan

PP025 The PARP inhibitor olaparib potentiates the effect of the DNA damaging agent doxorubicin in osteosarcoma
Jung Ryul Kim, Young Jae Moon
Chonbuk National University Medical School, Jeonju, South Korea

PP026 CEP55 promotes the proliferation and invasion of tumor cell via the AKT signaling pathway in osteosarcoma
Jin Xiong, Shoufeng Wang, Benlong Shi
Department of Orthopadic, Drum Tower Hospital, Nanjing University Medical School, Nanjing, China

PP027 Establishment and characterization of a novel osteosarcoma cell line: OSA 1777 FH
Pichaya Thanindratarn, Zhenfeng Duan
Department of Orthopedic Surgery, Sarcoma Biology Laboratory, David Geffen School of Medicine, University of California, Los Angeles, United States

PP028 Anti-tumor effect of the cyclic peptides derived from flaxseed against giant cell tumor of the bone
Yuta Taniguchi, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Hirotaka Yonezawa, Yoshihiro Araki, Sei Morinaga, Hiroyuki Tsuchiya
Department of Orthopaedic Surgery, Kanazawa University Hospital, Kanazawa, Japan

PP029 Effect of low- and high-linear energy transfer radiation on in vitro and orthotopic in vivo models of osteosarcoma by activation of caspase-3 and -9
Won-Seok Song, Chang-Bae Kong
Korea Cancer Center Hospital, Seoul, South Korea

PP030 Effects of mechanical loading on the degradability and mechanical properties of the nanocalcium-deficient hydroxyapatite–multi (amino acid) copolymer composite membrane tube for guided bone regeneration
Zeping Yu, Xiang Fang, Hong Duan
West China Hospital, Sichuan University, Chengdu, China

PP031 Analyzing the behavior of a porous nano-hydroxyapatite/polyamide 66 (n-HA/PA66) composite for healing of bone defects
Zeping Yu, Hong Duan, Xiang Fang
West China Hospital, Sichuan University, Chengdu, China

PP032 Revitalization of frozen autologous bone graft using adipose-derived stem cells
Yu Aoki¹, Norio Yamamoto¹, Katsuhiro Hayashi¹, Hiroaki Kimura¹, Akihiko Takeuchi¹, Shinji Miwa¹, Kentaro Igarashi¹, Hiroyuki Inatani¹, Takashi Higuchi¹, Kensaku Abe¹, Yuta Taniguchi¹, Yoshihiro Araki¹, Naotoshi Sugimoto², Hiroyuki Tsuchiya^1
1Department of Orthopaedic Surgery, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan; ²Department of Physiology, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan

PP033 Tumor-targeting Salmonella typhimurium A1-R is an effective general therapeutic for undifferentiated soft tissue sarcoma patient-derived orthotopic xenograft nude-mouse models
Kentaro Igarashi¹, Norio Yamamoto¹, Katsuhiro Hayashi¹, Hiroaki Kimura¹, Akihiko Takeuchi¹, Shinji Miwa¹, Takashi Higuchi¹, Yuta Taniguchi¹, Hirotaka Yonezawa¹, Yoshihiro Araki¹, Sei Morinaga¹, Robert Hoffman², Hiroyuki Tsuchiya^1
1Department of Orthopaedic Surgery, Kanazawa University, Kanazawa, Japan; ²Department of surgery, University of California San Diego, San Diego, United States

PP034 Newly developed bone targeting platinum complex effectively targets cisplatin resistant relapsed osteosarcoma in a patient-derived orthotopic xenograft (PDOX) mouse model
Kentaro Igarashi¹, Norio Yamamoto¹, Katsuhiro Hayashi¹, Hiroaki Kimura¹, Akihiko Takeuchi¹, Shinji Miwa¹, Takashi Higuchi¹, Yuta Taniguchi¹, Hirotaka Yonezawa¹, Yoshihiro Araki¹, Sei Morinaga¹, Robert Hoffman², Hiroyuki Tsuchiya^1
1Department of Orthopaedic Surgery, Kanazawa University, Kanazawa, Japan; ²Department of surgery, University of California San Diego, San Diego, United States

PP035 Relationship with adriamycin-resistant osteosarcomas and the pentose phosphate pathway using metabolomic approaches
Keita Sasa¹, Yoshiyuki Suehara¹, Keisuke Akaike¹, Takuo Hayashi², Hikari Taka³, Youngji Kim¹, Taketo Okubo¹, Kazuo Kaneko¹, Tsuyoshi Saito^2
1Orthopedic Surgery /Juntendo Univ., Tokyo, Japan; ²Human Pathology /Juntendo Univ., Tokyo, Japan; ³Laboratory of Proteomics and Biomolecular Science /Juntendo Univ., Tokyo, Japan

PP036 Preoperative lymphocyte count in relation to musculoskeletal sarcoma prognosis
Nor Faissal Yasin, Soon Teck, Vivek Ajit Singh
National Orthopaedic Centre of Excellence for Research and Learning (NOCERAL), University of Malaya, Kuala Lumpur, Malaysia

PP037 S1P promotes PDGF-A-dependent angiogenesis in human chondrosarcoma via Ras/Raf/MEK/ERK signaling cascade
Yi-Chin Fong^1,2, Chih-Hsin Tang^3
1Department of Orthopedic Surgery, China Medical University Beigang Hospital, Yunlin, Taiwan; ²Department of Orthopedic Surgery, China Medical University Hospital, Taichung, Taiwan; ³Department of Pharmacology, School of Medicine, China Medical University, Taichung, Taiwan

PP038 Comprehensive genomic profiling of patients with favorable prognosis in osteosarcoma
Weifeng Liu¹, Zhen Huang¹, Yanrui Zhang², Huina Wang², Yongkun Yang¹, Tao Jin¹, Xiaohui Niu^1
1Department of Orthopaedic Oncology Surgery, Beijing Ji Shui Tan Hospital, Peking University, Beijing, China; ²Acornmed Biotechnology Co., Ltd, Beijing, China

PP039 Epigenetic regulation of CXCL12 plays a critical role in mediating both tumor progression and the immune response in osteosarcoma
Binghao Li, Zhan Wang, Zhaoming Ye
The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China

PP040 Inhibitory effects of Indomethacin on human osteosarcoma tumor cells
Saied Mirshahidi^2,5, Rosalia de Necochea-Campion², Annie Moretta², Nadine Williams¹,Mark Reeves³, Salman Otoukesh⁴, Hamid Mirshahidi⁴, Duerksen-Hughes Penelope⁵, Lee Zuckerman^1
1Loma Linda University Medical Center, Department of Orthopaedic Surgery, Loma Linda, United States; ²Loma Linda University Medical Center, Cancer Center Biospecimen Laboratory, Loma Linda, United States; ³Loma Linda University Medical Center, Department of Surgical Oncology, Loma Linda, United States; ⁴Loma Linda University Medical Center, Division of Hematology/Oncology, Loma Linda, United States; ⁵Loma Linda University School of Medicine, Department of Basic Sciences, Loma Linda, United States

PP041 Tie-2 expressing monocytes are associated with rapid recurrence of giant cell tumor of bone
Yuwarat Monteerarat¹, Sorranart Muangsomboon², Rapin Phimolsarnti¹, Saranatra Waikakul¹,Chandhanarat Chandhanayingyong^1
1Department of Orthopaedic Surgery, Faculty of Medicine Siriraj Hospital, Bangkok, Thailand; ²Department of Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand

PP042 Comparative transcriptome analysis of primary tumor and matched tumor thrombus reveals that coagulation cascades activation contributes to the venous metastases of osteosarcoma
Tao Ji, Haijie Liang, Dasen Li, Wei Guo
Peking University, People's Hospital, Beijing, China

PP043 Infiltration of granulocytic myeloid derived suppressor cells compromises anti-PD-1 efficacy in osteosarcoma
Chuangzhong Deng, Yanyang Xu, Hongmin Chen, Huaiyuan Xu, Jin Wang
Musculoskeletal Department, Sun Yat-sen University Cancer Center, Guangzhou, China

PP044 Temozolomide arrests a doxorubicin-resistant follicular dendritic cell sarcoma patient-derived orthotopic xenograft (PDOX) mouse model
Hiromichi Oshiro¹, Yasunori Tome¹, Tasuku Kiyuna¹, Hiroki Maehara¹, Robert Hoffman², Fuminori Kanaya^1
1Department of Orthopedic Surgery, Graduate School of Medicine, University of the Ryukyus, Nishihara-cho, Japan; ²Department of Surgery, University of California, San Diego, San Diego, United States

PP045 High efficacy of combination therapy of mTOR inhibitor and VEGFR inhibitor against doxorubicin resistant osteosarcoma using patient-derived orthotopic xenograft model
Hiromichi Oshiro^1,2, Yasunori Tome¹, Tasuku Kiyuna¹, Hiroki Maehara¹, Robert Hoffman², Fuminori Kanaya^1
1Department of Orthopedic Surgery, Graduate School of Medicine, University of the Ryukyus, Nishihara-cho, Japan; ²Department of Surgery, University of California, San Diego, San Diego, United States

PP046 Integrative analysis including whole genome sequencing, transcriptome sequencing, and phospho-protein expression profiling of super responder to pazopanib in high-grade soft tissue sarcomas
Yoshiyuki Suehara¹, Shinji Kohsaka², Shigeo Yamaguchi³, Takuo Hayashi⁴, Taisei Kurihara¹, Keisuke Akaike¹, Toshihide Ueno², Shinya Kojima², Masachika Ikegami², Sho Mizuno², Kazuo Kaneko¹, Shunsuke Kato³, Hiroyuki Mano², Tsuyoshi Saito^4
1Department of Orthopedic Surgery, Juntendo University School of Medicine, Tokyo, Japan; ²Division of Cellular Signaling, National Cancer Center Research Institute, Tokyo, Japan; ³Department of Medical Oncology, Juntendo University School of Medicine, Tokyo, Japan; ⁴Department of Human Pathology, Juntendo University School of Medicine, Tokyo, Japan

PP047 The role of Frozen-Nitrogen-Ethanol-Liquid-Composite in Metal-implant-related infections. Shinning a New light on Biofilm-eradication
Wang Jir-You^1,2,3, Wu Po-Kuei^1,2, Chen Chao-Ming^1,2, Chen Wei-Ming^1,2
1Department of Orthopaedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan; ²Department of Orthopaedics, Therapeutical and Research Center of Musculoskeletal Tumor, Taipei Veterans General Hospital, Taipei, Taiwan; ³Institutes of Traditional Medicine, National Yang- Ming University, Taipei, Taiwan

PP048 Targeting mutant TP53 as a potential therapeutic strategy for the treatment of osteosarcoma
Fan Tang, Li Min, Wenli Zhang, Rui Shi, Yong Zhou, Yi Luo, Hong Duan, Chongqi Tu
Department of Orthopeadic, West China Hospital, Sichuan University, Chengdu, China

PP049 MicroRNA-429 inhibits bone metastasis in breast cancer by regulating CrkL and MMP-9
Xinxin Zhang¹, Xiying Yu¹, Zhenguo Zhao¹, Zhennan Yuan¹, Zhibin Ye², Songfeng Xu¹, Libin Xu¹, Ting Liu¹, Shih-Hsin Lu¹, Shengji Yu^1
1Department of Orthopaedics/National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; ²Department of Gastrointestinal Surgery/Hebei General Hospital, Shijiazhuang, China

PP050 Comparative study evaluating open versus arthroscopic treatment for tenosynovial giant cell tumors of the foot and ankle
Shinji Tsukamoto¹, Riccardo Zucchini², Eric Staals², Andreas Mavrogenis³, Manabu Akahane⁴, Emanuela Palmerini⁵, Costantino Errani², Kanya Honoki¹, Akira Kido¹, Yasuhito Tanaka^1
1Department of Orthopaedic Surgery, Nara Medical University, Kashihara-city, Japan; ²Department of Orthopaedic Oncology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy; ³First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece; ⁴Department of Public Health, Health Management and Policy, Nara Medical University, Kashihara-city, Japan; ⁵Chemotherapy Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy

PP051 Radiological assessment for pathogenesis of solitary bone cyst in calcaneus
Manabu Hoshi, Naoto Oebisu, Tadashi Iwai, Akiyoshi Shimatani, Naoki Takada, Hiroaki Nakkamura
Department of Orthopedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan

PP052 Do curettage and cementation can provide local control of Fibrous dysplasia of the proximal radius?
Ismail Tawfeek Badr¹, Rampal Sanjiv², Ahmed Shaheen^1
1Menoufia University Faculty of Medicine, Orthopedic Departement, Menoufia, Egypt; ²Putra University, Faculty of Medicine, Orthopedic Department, Malaysia

PP053 A rare case of posterior tibial nerve schwannoma causing tarsal tunnel syndrome
Levent Berkem¹, Sefa Giray Batibay², Mehmet Esat Uygur³, Korhan Özkan^3
1Goztepe Training and Research Hospital, Department of Orthopaedics and Traumatology, Istanbul, Turkey; ²Orthopaedics and Traumatology, Derince Training and Research Hospital, Kocaeli, Turkey; ³Orthopaedics and Traumatology, School of Medicine, Medeniyet University, Istanbul, Turkey

PP054 Periosteal aneurysmal bone cyst involving proximal femur
Levent Berkem¹, Korhan Özkan², Zilan Karadağ^2
1Goztepe Training and Research Hospital, Department of Orthopaedics and Traumatology, Istanbul, Turkey; ²Department of Orthopaedics and Traumatology, School of Medicine, Medeniyet University, Istanbul, Turkey

PP055 Successful total en bloc spondylectomy of the L3 vertebra with a paravertebral giant cell tumor following preoperative treatment with denosumab
Hideyuki Kinoshita, Tsukasa Yonemoto, Hiroto Kamoda, Toshinori Tsukanishi, Yoko Hagiwara, Takeshi Ishii
Chiba Cancer Center, Chiba, Japan

PP056 Giant muscle invasive dermatofibroma clinically mimicking a malignant tumor
Hideyuki Kinoshita, Takeshi Ishii, Hiroto Kamoda, Toshinori Tsukanishi, Yoko Hagiwara, Tsukasa Yonemoto
Chiba Cancer Center, Chiba, Japan

PP057 Clinical features of chondroblastoma: A review of 18 cases
Toru Hirozane¹, Naofumi Asano¹, Kazutaka Kikuta², Michiro Susa³, Itsuo Watanabe⁴, Takeshi Morii⁵, Masaya Nakamura¹, Morio Matsumoto¹, Robert Nakayama^1
1Department of Orthopedic Surgery, Keio University School of Medicine, Tokyo, Japan; ²Department of Musculoskeletal Oncology and Orthopaedic Surgery, Tochigi Cancer Center, Utsunomiya, Japan; ³Department of Orthopedic Surgery, National Defense Medical College, Tokorozawa, Japan; ⁴Department of Orthopedic Surgery, Tokyo Dental College Ichikawa General Hospital, Ichikawa, Japan, ⁵Department of Orthopedic Surgery, Kyorin University Hospital, Mitaka, Japan

PP058 Rare benign bone tumour in rare location
Salim Al-Busaidi
AFH Oman, Muscat, Oman

PP059 Rare tumor of foot
Salim Al-Busaidi
Armed Forces Hospital (AFH), Al-Seeb, Oman

PP060 Direct femoral head approach without dislocation (modified trapdoor procedure) for femoral head chondroblastoma
Hirohisa Katagiri, Mitsuru Takahashi, Hideki Murata, Junji Wasa, Michihito Miyagi
Division of Orthopaedic Oncology, Shizuoka Cancer Center Hospital, Nagaizumi-cho, Japan

PP061 Minimal invasive direct anterior approach versus standard lateral approach in the management of tumor located in the femoral neck
Bo Wang
The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

PP062 Ethanol as the intra-operative adjuvant in giant cell tumor of bone surgery
Wei-Hsin Lin¹ , Shau-Huai Fu², Chia-Che Lee¹, Hsiang-Chieh Hsieh³, Shin-Yin Lin¹, Rong-Sen Yang^1
1Department of Orthopedics, National Taiwan University Hospital, Taipei City, Taiwan; ²Department of Orthopedics, National Taiwan University Hospital Yun-Lin Branch, Yun-Lin County, Taiwan, ³Department of Orthopedics, National Taiwan University Hospital Hsinchu Branch, Hsinchu City, Taiwan

PP063 En block resection and osteoarticular allograft reconstruction of Grade 3 giant cell tumor of bone. Long term follow-up results
Jose Ignacio Albergo, German Farfalli, Angeles Cabas-Geat, Miguel Ayerza, Pablo Roitman, Luis Aponte-Tinao
Hospital Italiano De Buenos Aires, Caba, Argentina

PP064 Clinical results of treatment for recurrent giant cell tumors of bone after administrated denosumab and curettage
Osamu Dohi¹, Masahito Hatori¹, Masami Hosaka², Koshi Kishimoto¹, Satoshi Kotajima¹, Mika Watanabe³, Shin Hitachi^4
1Dept. of Orthop. Surg., Tohoku Kosai Hospital, Sendai, Japan; ²Dept. of Orthop. Surg., Miyagi Cancer Center, Sendai, Japan; ³Dept. of Pathol., Tohoku Univ. Hosp., Sendai, Japan; ⁴Dept. of Diag., Radiol., Tohoku Univ. Hosp., Sendai, Japan

PP065 Does the percutaneous sclerotherapy with absolute alcohol present a safe and efficient treatment of the aneurysmal bone cysts by children?
Rodanthi Margariti, Panagiotis Kolovos, Eftichios Papagrigorakis, Nikolaos Kotsakis, Dimitris Papadopoulos, Christos Babouris, Panagiotis Sourilas, Panagiotis Megremis, Christos Zambakides
General Children's Hospital of Athens "P & A Kiriakou", Athens, Greece

PP066 Treatment of benign tumors of femur neck by extended Watson Jones approach combined with superior-gluteal-vessels-gluteus-minimus-greater-trochanter-bone-flap (SGVGMGTBF)
Shuangwu Dai, Haomiao Li, Zixiong Lei, Changhe Hou
The Third Affiliated Hospital of Southern Medical University, Guangzhou, China

PP067 Tumor-Induced Osteomalacia (TIO): A rare case report of adolescent-onset (18 years old) hypophosphatemic osteomalacia
Puwadon Veerapan
Phramongkutklao Hospital, Bangkok, Thailand

PP068 Clinical outcome in patients with bone tumor using calcium phosphate cement following more than 5 years
Tomohito Hagi, Tomoki Nakamura, Kunihiro Asanuma, Koji Kita, Akihiro Sudo
Mie University, Tsu City, Japan

PP069 Treatment of osteofibrous dysplasia in a 13-month old child with curettage and placement of allograft bone
Nadine Williams, Omar Ramos, Alex Mierke, Lee Zuckerman
Loma Linda University Medical Center, Department of Orthopaedic Surgery, Loma Linda, United States

PP070 Pseudoaneurysm of popliteal artery branch in distal femur osteochondroma
Mohamed Hafizudin Abdullah Sani, Mohamad Hilmi Mohamad Nazarallah
UKMMC, Shah Alam, Malaysia

PP071 Clinical outcome of giant cell tumor of bone of the proximal fibula
Masato Saito¹, Kazutaka Kikuta², Yoshihisa Suzuki³, Hideo Morioka⁴, Naofumi Asano¹, Masaya Nakamura¹, Morio Matsumoto¹, Robert Nakayama^1
1Department of Orthopaedic Surgery, Keio University School of Medicine, Tokyo, Japan; ²Department of Musculoskeletal Oncology and Ortopaedic Surgery, Tochigi Cancer Center, Tochigi, Japan; ³Department of Orthopaedic Surgery, Tachikawa Hospital, Tokyo, Japan; ⁴Department of Orthopaedic Surgery, National Hospital Organization Tokyo Medical Center, Tokyo, Japan

PP072 Proximal femur giant cell tumor: When to conserve and when to replace
Florencio Vicente Segura, Florencio Pablo Segura, Facundo Manuel Segura
National University of Córdoba. Department of Orthopaedics., Córdoba, Argentina

PP073 Lesions in tuberosity of tibia that mimicking Osgood-Schlatter disease
Masoud Mirkazemi, Khodamorad Jamshidi
Iran University of Medical Sciences, Tehran, Iran

PP074 Thrombosed popliteal artery pseudoaneurysm as presentation sign of a solitary osteochondroma
Laura Izquierdo¹, Salvador Ausina, Alberto Miñano², María Carmen Castro¹, María José Mayol¹, Iván Pérez
¹San Juan University Hospital, Alicante, Spain; ²Alicante General University Hospital, Alicante, Spain

PP075 Secondary osteoarthritis and its risk factors after curettage and augmentation with calcium phosphate cement for giant cell tumor of bone around the knee joint
Yoshihiro Araki, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Takashi Higuchi, Kensaku Abe, Yuta Taniguchi, Hirotaka Yonezawa, Sei Morinaga, Hiroyuki Tsuchiya
Kanazawa University Hospital, Kanazawa City, Japan

PP076 Intralesional curettage for giant cell tumor of bone around the knee
Wanlim Kim, Jong-seok Lee
Asan Medical Center, Seoul, South Korea

PP077 Human Dirofilaria of subcutaneous tissue of the thigh mimicking soft tissue tumor - A case report
Ahmed Elramadi, Syed Alam, Ahmed Elsayed, Hasan Abuhejleh
Hamad Medical Corporation, Doha, Qatar

PP078 Spontaneous hyperplastic callus formation in osteogenesis imperfecta, mimicking chondrogenic bone tumor
David Yung, Masato Saito, Toru Hirozane, Naofumi Asano, Robert Nakayama
Department of Orthopaedic Surgery, Keio University School of Medicine, Tokyo, Japan

PP079 “UmbrellaConstruct” – An innovative technique for locally aggressive benign bone tumors of proximal humerus
Ashish Gulia, Srinath Gupta, Vineet Kurisunkal, Ajay Puri
Tata Memorial Hospital, Mumbai, India

PP080 Comparison of point counting and planimetry methods for estimation of bone cyst volume using computer tomography images: A stereological study
Murat Golpinar¹, Ferhat Say², Nuket Gocmen Mas³, Bunyamin Sahin^4
1Department of Anatomy, Faculty of Medicine, Hitit University, Çorum, Turkey; ²Department of Orthopaedics and Traumatology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey; ³Department of Anatomy, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey; ⁴Department of Anatomy, Faculty of Medicine, Gazi Osmanpaşa University, Tokat, Turkey

PP081 Case series of Dermatofibrosarcoma Protuberans in a single institution
David Alejandro Herrera, Olavo Pires de Camargo, Andre Mathias, Daniel Rebolledo, Luiz Filipe Correia, AndreFerrari, Marcelo Tadeu
Universidade De Sao Paulo (Hospital Das Clínicas), Sao Paulo, Brazil

PP082 Recurrent giant cell tumors of bones - Management principles and functional outcome in a series of 24 patients
Umesh Yadav
Pgims Rohtak, Rohtak, India

PP083 Osteoid osteoma of the triquetrum: case report of an unusual tumor location
Alparslan Yurtbay¹, Hikmet Çinka¹, Ferhat Say¹, Sancar Barış², Fevziye Canbaz Tosun³, Sibel Uçak Semirgin^3
1Department of Orthopedic and Traumatology, Ondokuz Mayis University Hospital, Samsun, Turkey; ²Department of Pathology, Ondokuz Mayis University Hospital, Samsun, Turkey; ³Department of Nuclear Medicine, Ondokuz Mayis University Hospital, Samsun, Turkey

PP084 Long-term functional outcomes of distal femoral replacements compared to geographic resections for parosteal osteosarcomas of the distal femur
Benjamin Wilke¹, Anna Cooper³, C. Parker Gibbs², Mark Scarborough², Andre Spiguel^2
1Mayo Clinic, Jacksonvile, United States; ²University of Florida, Gainesville, United States; ³Loyola University, Chicago, United States

PP085 Physeal distraction during surgical treatment of osteosarcoma of the femur
Yao Weitao
He Nan Cancer Hospital, Zheng Zhou City, China

PP086 Prognosis analysis of preoperative arteriovenous dual pathway chemotherapy in limb salvage surgery of osteosarcoma
Shiquan Zhang, Wei You, Chuanxi Zheng, Hao Chen
Shenzhen University First Affiliate Hospital, Shenzhen, China

PP087 Expression of vascular endothelial growth factor (VEGF) in osteosarcoma patients
Djamila Polatova
Republican Specialized Scientific-Practical Medical Centre of Oncology and Radiology, Ministry of Healthcare, Tashkent, Uzbekistan

PP088 Drug resistance as an important prognostic factor in osteosarcoma
Djamila Polatova
Republican Specialized Scientific-Practical Medical Centre of Oncology and Radiology, Ministry of Healthcare, Tashkent, Uzbekistan

PP089 Chondrosarcoma of the shoulder girdle behave differently depending on the location of the tumour
Minna Laitinen¹, Jose Albergo², Jonathan Stevenson³, German Farfalli², Luis Aponte-Tinao², Lee Jeys³, Michael Parry^3
1Helsinki University Hospital, Helsinki, Finland; ²Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; ³Royal Orthopaedic Hospital, Birmingham, United Kingdom

PP090 Hemicortical resection indications in parosteal osteosarcoma
Osman Emre Aycan¹, Harzem Özger², Bugra Alpan³, Natig Valiyev^1
1Orthopaedics and Traumatology, Acibadem Maslak Hospital, Istanbul, Turkey; ²Istanbul Orthopaedic Oncology Group, Istanbul, Turkey; ³Orthopaedics and Traumatology, Mehmet Ali Aydinlar University, Istanbul, Turkey

PP091 Clinical outcome of dedifferentiated low-grade osteosarcoma
Eisuke Kobayashi¹, Shunichi Toki¹, Akihiko Yoshida², Akira Kawai^1
1Dept. of Musculoskeletal Oncology National Cancer Center Hospital, Tokyo, Japan; ²Dept. of Pathology and Clinical Laboratories, National Cancer Center Hospital, Tokyo, Japan

PP092 Osteosarcoma as secondary malignancy in patients following retinoblastoma
Yongsung Kim¹, Woo Young Jang³, Ilkyu Han¹, Hwan Seong Cho², Han-Soo Kim^1
1Department of Orthopaedic Surgery, Seoul National University Hospital, Seoul, South Korea; ²Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, Seongnam, South Korea; ³Department of Orthopaedic Surgery, Korea University Anam Hospital, Seoul, South Korea

PP093 Potential molecular biological markers of tumor growth in osteosarcoma
Djamila Polatova, Mirza Gafur-Akhunov, Nargiza Karimova
Republican Specialized Scientific-Practical Medical Centre of Oncology and Radiology, Ministry of Healthcare, Tashkent, Uzbekistan

PP094 Distant soft tissue metastasis in a patient of osteosarcoma distal femur with pulmonary metastases
Roshan Banjara, Sushma Thapa, Abdul Majeed, Venkatesan Sampath Kumar, Shah Alam Khan
Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi, India

PP095 Ewing’s sarcoma of the lumbar spine in an adult
Abigail Tud, Richard Rotor
Philippine Orthopedic Center, Quezon City, Philippines

PP096 Biological reconstruction of the bone in bone sarcoma in children using external fixation systems
Panagiotis Kolovos, Margariti Rodanthi, Dimitrios Papadopoulos, Panagiotis Sourilas, Panagiotis Megremis, Christos Zambakides
General Hospital of Children "Aglaia Kyriakou", Athens, Greece

PP097 The effect of type of surgery for outcome in low-grade chondrosarcoma
Edwin Dierselhuis¹, Krista Goulding², Martin Stevens³, Paul Jutte^3
1Department of Orthopaedics, Radboudumc, Nijmegen, Netherlands; ²Department of Orthopaedics, Mayo Clinic- Arizona, Phoenix, United States; ³Department of Orthopaedics, University Medical Center Groningen, University of Groningen, Groningen, Netherlands

PP098 Μetastasis in the contralateral epiphysis in distal femoral osteosarcoma patients: A report of two cases
Ioannis Papanastassiou¹, Olga Savvidou², Kostantinos Tolis³, Nikolaos Stavropoulos², John Healey⁴, Panayiotis Papagelopoulos^2
1General Oncological Hospital Kifisias "Agioi Anargyroi", Athens, Greece; ²First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, School of Medicine, “Attikon” University General Hospital, Athens; Greece, ³Hand surgery/Upper limb Microsurgery Department, General Hospital KAT, Athens, Greece; ⁴Memorial Sloan Kettering Cancer Center, Athens, Greece

PP099 What is the current trend of treatment for high-grade osteosarcoma? Limb salvage surgery versus amputation: A systematic review
Sherly Desnita Savio, Maria Florencia Deslivia, I Gede Eka Wiratnaya
Orthopaedics and Traumatology Department, Faculty of Medicine Udayana University, Sanglah General Hospital, Denpasar, Indonesia

PP100 Osteosarcoma in elderly patients: a report of 10 cases
Ka Li, Jianmin Li, Zhiping Yang, Xin Li, Zhenfeng Li, Qiang Yang
Department of Orthopedics, Qilu Hospital of Shandong University, Jinan, China

PP101 The combination of amygdalin with some anti-cancer, anti-parasitic, and anti-inflammatory drugs against MG63 and FL cells in vitro
Davut Aydın¹, Ali Aydın², Korhan Özkan³, Fuat Akpınar³, Şaban Tekin^4
1Kayseri State Hospital, Kayseri, Turkey; ²Tuzla State Hospital İstanbul, Turkey; ³Medeniyet University, İstanbul, Turkey; ⁴University of Health Sciences, İstanbul, Turkey

PP102 Functional and oncological outcomes in extraarticular resection and reconstruction limb salvage surgery for bone and soft tissues involving the joint
Kishore Reddy^1,2,3, Rajashekar Danda², Pavan Murari², Abhilash Kumar^3
1American Oncology Institute, Hyderabad, India; ²Omni Hospital, Hyderabad, India; ³Citizens Hospital, Hyderabad, India

PP103 Primary bone leiomyosarcoma in distal femur metastatic to clavicle: A case report
Francisco Linares¹, Helbert Martin¹, Natalia Correal
¹Orthopedics Department, Pontificia Universidad Javeriana, Hospital Universitario San Ignacio, Bogotá, Colombia; ²Medical Faculty Pontificia Universidad Javeriana, Bogotá, Colombia

PP104 Synchronous multicentric osteosarcoma: A report of 5 cases
Yoshihiro Araki, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Takashi Higuchi, Kensaku Abe, Yuta Taniguchi, Hirotaka Yonezawa, Sei Morinaga, Hiroyuki Tsuchiya
Kanazawa University Hospital, Kanazawa City, Japan

PP105 C-reactive protein and neutrophil counts as a predictor of metastasis in patients with osteosarcoma
Yoshihiro Araki, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Takashi Higuchi, Kensaku Abe, Yuta Taniguchi, Hirotaka Yonezawa, Sei Morinaga, Hiroyuki Tsuchiya
Kanazawa University Hospital, Kanazawa City, Japan

PP106 Does preoperative radiotherapy reduce recurrence rates and increase survival in high grade osteosarcoma of the extremities?
Mahmut Kursat Ozsahin¹, Murat Hiz¹, Bedri Karaismailoglu², Suat Ulutas^1
1Cerrahpasa Medical Faculty Orthopaedics And Traumatology, Istanbul, Turkey; ²Sinop Ayancik State Hospital, Sinop, Turkey

PP107 Long-term follow-up of 7 periosteal Ewing ‘cases. Key points for surgery
Fabrice Delepine¹, Gerard Delepine^2
1Clinique Du Parc Imperial, Nice, France; ²APHP (retired), Drancy, France

PP108 Chondrosarcoma: clinical features, follow up and prognostic factors. Twenty years of experience in a single institution
Juan Pablo Zumarraga¹, André Mathias Baptista², Whinsgton Pereira de Souza², David Herrera Moreano², Olavo Pires de Camargo^2
1Departamento de Ortopedia y Traumatología, Hospital de los Valles, Universidad San Francisco de Quito, Quito, Ecuador; ²Grupo de Oncologia Ortopedica, Instituto de Ortopedia e Traumatologia, Hospital das Clinicas, Universidade de São Paulo, São Paulo, Brasil

PP109 Primary intra osseous synovial sarcoma: A series of 7 cases with review of literature
Vishnu Ramanujan, Anand Raja, Chandrakumar Krishnan, Mayilvahanan Natrajan
Cancer Institute (WIA), Adyar, Chennai, India

PP110 Biological extramedullary fixation in limb salvage surgery with HA collars
Ioannis Papakostas, Giakoumis Diakoumis, Serafeim Sarafopoulos, Spyros Valvis, Sofia Dara, Theodoros Kormas
Department of Orthpedic Surgery and Oncology, St. Savvas Hospital, Athens, Greece

PP111 Extremity chondrosarcoma - Survival and prognostic factors in South Indian patients
Chandra Kumar Krishnan, Vishnu Ramanujan, Anand Raja, Mayilvahanan Natarajan
Cancer Institute (WIA), Chennai, India

PP112 Relationship between height at diagnosis and Osteosarcoma in the Indian population
Venkatesan Sampath Kumar, Roshan Banjara, Rishi Ram Poudel, Abdul Majeed, Muthu Kumaran, Shah Alam Khan
Dept. of Orthopaedics, All India Institute of Medical Sciences, New Delhi, India

PP113 Funcitonal and oncological outcomes of surgical resection of malignant primary clavicle tumors
Srinath Gupta, Ashish Gulia, Prakash Nayak, Ajay Puri, Vineet John Kurisunkal, Prateek Hegde, Ashwin Prajapati, Navaneeth Kamath
Tata Memorial Hospital, Mumbai, India

PP114 Syncronic multifocal osteosarcoma affecting distal femur: One case long term follow-up
Adriana Hernandez¹, Carlos Eduardo Cuervo Lozano², Alejandro Sanchez Hernandez^1
1Centro Medico Zambrano Hellion, Tec Salud, Monterrey, Mexico; ²Departamento de Ortopedia y Traumatología, Hospital "Dr. José Eleuterio González" Universidad Autónoma de Nuevo León, Monterrey, México

PP115 Adamantinoma: Long-term follow-up study of 20 patients treated at a single institution
Daniel Prince, Eugenia Schwarzkopf, Yoely Tavarez, John H. Healey, Narasimhan Agaram, Molly Klima
Memorial Sloan Kettering Cancer Center, New York, United States

PP116 Preoperative surgical risk stratification in osteosarcoma based on the proximity to the major vessels
Tomohiro Fujiwara, Manuel Medellin, Andrea Sambri, Jan Balko, Vaiyapuri Sumathi, Yusuke Tsuda, Scott Evans, Jonathan Stevenson, Michael Parry, Jonathan Gregory, Lee Jeys, Adesegun Abudu
Royal Orthopaedic Hospital, Birmingham, United Kingdom

PP117 The dilemma Surgery/Radiotherapy in Children with Ewing sarcoma of bone
Marco Manfrini¹, Silvia Cammelli², Massimo Eraldo Abate¹, Alessandra Longhi¹, Laura Campanacci¹, Davide Donati^1
1Istituto Ortopedico Rizzoli, Bologna, Italy; ²Radiation Oncology Center - DIMES - University of Bologna, Bologna, Italy

PP118 Neuropathic pain among musculoskeletal tumor patients treated at a Tertiary Care Referral Center in Malaysia
Azura Mansor, Rishi Ram Poudel, Mandeep Pratak, Nor Faissal Yasin, Vivek Ajit Singh
University of Malaya Medical Centre, Kuala Lumpur, Malaysia

PP119 3 year follow-up of recurrent inflammatory myofibroblastic tumor of the posterior neck in a 53 year old male - A case report
Emmanuel Roy Mata¹, Ryan Conrad Carnero^1,2
1The Medical City Department of Orthopedics, Pasig City, Philippines; ²Philippine Orthopedic Center, Quezon City, Philippines

PP120 When to resect: Fixed or flexible neoadjuvant chemotherapy
Sudhir Kumar Garg, Kisley Dimri, Purnima Aggarwal, Rajinder Pal Singh Punia
Government Medical College & Hospital, Chandigarh, India

PP121 A single-institution retrospective study: Clinical outcome of pazopanib for the treatment of soft-tissue sarcomas
Naoki Takada, Naoto Oebisu, Manabu Hoshi, Tadashi Iwai, Akiyoshi Shimatani, Hiroaki Nakamura
Dept. of Orthopedic Surgery, Osaka City University, Graduate School of Medicine, Osaka, Japan

PP122 Complete regression of metastatic embryonal rhabdomyosarcoma in a young adult secondary to postoperative wound infection following limb salvage surgery
Andrew Fang, Lee Jae Morse
The Permanente Medical Group, Oakland, United States

PP123 Phase I/II study of immunotherapy with dendritic cells pulsed with autologous tumor lysate in patients with refractory sarcoma
Shinji Miwa, Hideji Nishida, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Takashi Higuchi, Yuta Taniguchi, Hirotaka Yonezawa, Sei Morinaga, Hiroyuki Tsuchiya
Department of Orthopaedics, Kanazawa University, Kanazawa, Japan

PP124 High dose chemotherapy and autologous stem cell transplantation improves survival of patients with osteosarcoma which respond poorly to neoadjuvant chemotherapy
Che Ry Hong¹, Kyung Taek Hong¹, Jung Yoon Choi¹, Han-Soo Kim², Yongsung Kim², Sung-Hye Park³, Hyoung Jin Kang¹, Hee Young Shin^1
1Division of Hematology/Oncology, Department of Pediatrics, Cancer Research Institute, Seoul National University College of Medicine, Seoul National University Children’s Hospital, Seoul, South Korea; ²Department of Orthopaedic Surgery, Seoul National University College of Medicine, Seoul, South Korea; ³Department of Pathology, Seoul National University College of Medicine, Seoul, South Korea

PP125 Efficacy of neoadjuvant chemotherapy for Synovial sarcoma: Retrospective analysis based on a nationwide database
Hisaki Aiba^1,2, Satoshi Yamada¹, Xu Gang², Norio Yamamoto², Hiroyuki Tsuchiya², Hideki Murakami¹, Akira Kawai^3
1Nagoya City University, Nagoya, Japan; ²Kanazawa University, Kanazawa, Japan; ³National Cancer Center, Tokyo, Japan

PP126 Outcomes of treatment of compartment syndrome in orthopedic oncology patients
Alysia Kemp¹, Sydney Singleterry², Tam Huynh¹, Valerae Lewis¹, Robert Satcher^1
1The University of Texas MD Anderson Cancer Center, Houston, United States; ²University of Texas Southwestern Medical School, Dallas, United States

PP127 Perioperative surgical antibiotic prophylaxis in prthopaedic oncology: Which antibiotic is adequate for resection of soft tissue sarcomas in the adductor and gluteal area
Alexander Klein¹, Chataut Chudamani¹, Volkmar Jansson², Hans Roland Dürr^1
1Orthoaedic Oncology, Department of Orthopaedics, Physical Medicine and Rehabilitation, University Hospital, LMU Munich, Munich, Germany; ²Department of Orthopaedics, Physical Medicine and Rehabilitation, University Hospital, LMU Munich, Munich, Germany

PP128 Risk factors for wound complications following resection of high-grade soft tissue sarcomas
Ryuta Iwanaga
Department of Orthopedic Surgery, Yamaguchi University School of Medicine, Ube, Japan

PP129 Complication profiles in secondary revisions of tumor endoprosthetic reconstruction around the knee
Bugra Alpan¹, Osman Emre Aycan², Natig Valiyev², Harzem Özger^3
1Orthopaedics and Traumatology, Mehmet Ali Aydinlar University Faculty of Medicine, Istanbul, Turkey; ²Orthopaedics and Traumatology, Acibadem Maslak Hospital, Istanbul, Turkey; ³Istanbul Orthopaedic Oncology Group, Istanbul, Turkey

PP130 Postoperative complications, functional and clinical outcome of elderly patients with primary high grade malignant musculoskeletal tumors
Masato Sugawara, Daiichiro Takahara, Hiromori Sagae, Michiaki Takagi
Department of Orthopaedic Surgery, Yamagata University Faculty of Medicine, Yamagata, Japan

PP131 Revision megaendoprosthetic reconstructions after tumor prosthesis replacement
Oleg Vyrva
Sytenko Institute of Spine and Jointh Pathology, Kharkiv, Ukraine

PP132 Sarcopenia is associated with increased mortality and complications following sarcoma resection in the extremities
Benjamin Miller, Nathan Hendrickson
University of Iowa, Iowa City, United States

PP133 Implant and limb survival after resection of bone tumors of the lower extremities and reconstruction with mega-prostheses
Christina Holm, Michala Skovlund Sørensen, Müjgan Yilmaz, Michael Mørk Petersen
Musculoskeletal Tumor Section, Department of Orthopaedic Surgery, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

PP134 Silver-coated versus standard endoprostheses in the treatment of lower extremity osteosarcomas – A cost-effectiveness analysis
Dipak B. Ramkumar^1,2, Marcel Brown², Niveditta Ramkumar³, David Jevsevar^1,2
1Department of Orthopaedic Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, United States; ²Geisel School of Medicine at Dartmouth, Hanover, United States; ³The Dartmouth Institute, Lebanon, United States

PP135 Revision of custom 3D printed pelvic implants – Lessons learned
Richard Boyle¹, Daniel Franks¹, Natalie Bennell^2
1Royal Prince Alfred Hospital Sarcoma Unit, Sydney, Australia; ²OSSIS, Christchurch, New Zealand

PP136 Surgical management of pathological fractures of the femur after radiation therapy due to soft tissue tumor
Wanlim Kim, Jung-Jae Kim, Jong-Seok Lee
Asan Medical Center, Seoul, South Korea

PP137 Long term results of infected massive prostheses treatment by high dose vancomycin loaded spacers
Fabrice Delepine¹, Gerard Delepine², Salwa Alkhallaf^3
1Clinique Du Parc Imperial, Nice, France; ²APHP (retired), Drancy, France, ³Centre Médicosocial, Paris, France

PP138 Implant survival and mode of failure of tumour endoprosthesis after lower limb tumour resection
Takeshi Hirose, Shintaro Iwata, Fumihiko Nakatani, Eisuke Kobayashi, Takeshi Komatsubara, Jun Sugaya, Akira Kawai
National Cancer Center Hospital, Tokyo, Japan

PP139 Salvage limb salvage in lower limb reconstruction with Megasystem C
Francesco Muratori¹, Filippo Frenos¹, Guido Scoccianti¹, Maurizio Scorianz¹, Xhulio Prifti¹, Alberto Schiavo¹, Saverio Bartolini¹, Giovanni Beltrami², Rodolfo Capanna³, Domenico Andrea Campanacci^1
1Department of Orthopedic Oncology and Reconstructive Surgery, Firenze, Italy; ²Department of Paediatric Orthopaedic Oncology, Careggi Universitary Hospital, Firenze, Italy; ³Clinic of Orthopaedics and Traumatologyl, University of Pisa, Pisa, Italy

PP140 Medium term structural Failure in proximal tibial endoprosthesis - Report of two cases
Sahran Yahaya, Wan Faisham Wan Ismail, Norazman Mat Zin
Universiti Sains Malaysia, Kota Bharu, Malaysia

PP141 Total femoral reconstruction after sarcoma resection, a retrospective analysis of 31 patients
Julian Röder, Jan Christoph Theil, Georg Gosheger, Jan Schwarze, Kristian Nikolaus Schneider, Thomas Ackmann, Niklas Deventer, Dimosthenis Andreou
Universitätsklinikum Münster Klinik für Allgemeine Orthopädie und Tumororthopädie, Münster, Germany

PP142 Bone cement pulmonary embolism - A case report
Navaneeth Kamath, Ashish Gulia, Ajay Puri, Prakash Nayak, Prateek Hegde, Srinath Gupta, Ashwin Prajapati, Vineet Kurisunkal
Tata Memorial Hospital, Mumbai, India.

PP143 Use of antibiotic spacers for knee endoprosthesis infections treatment
Dan Viola, Reynaldo Jesus-Garcia, Jairo Garcia, Henrique Rodrigues, Vinicius Mazzolin, Nathalia Oliveira
UNIFESP/GRAACC, São Paulo, Brazil

PP144 Diagnosing soft tissue tumors – Are radiology reports from non-cancer centers equally precise?
Ana C. Belzarena¹, Michael D'Angelo², Douglas Letson¹,David Joyce^1
1Sarcoma Department, University of South Florida, Moffitt Cancer Center, Tampa, United States; ²Morsani College of Medicine, University of South Florida, Tampa, United States

PP145 Incremental direct imaging costs due to non-referring sarcoma patients
Ana Belzarena¹, Cecilia Belzarena¹, Michael D'Angelo², David Joyce^1
1Sarcoma Department, University of South Florida, Moffitt Cancer Center, Tampa, United States; ²Morsani College of Medicine, University of South Florida, Tampa, United States

PP146 Evaluation of interobserver reliabilty between MRI features and histopathological findings in soft tissue sarcoma
Nor Hazla Mohamed Haflah, Way Siong Ho, Sharifah Majedah Idrus Alhabshi, Abdul Yazid Mohd Kassim
Universiti Kebangsaan Malaysia, Cheras, Malaysia

PP147 Prediction of response to neoadjuvant chemotherapy in osteosarcoma using Dual-phase 18F-FDG PET/CT
Chang-Bae Kong, Byung Hyun Byun, Won Seok Song
Korea Cancer Center Hospital, Seoul, South Korea

PP148 Development of multifocal extra-abdominal desmoid fibromatosis after surgical resection
Nadine Williams, Omar Ramos, Alex Mierke, Lee Zuckerman
Loma Linda University Medical Center, Department of Orthopaedic Surgery, Loma Linda, United States

PP149 Intracardiac migration of a steinman pin after shoulder arthrodesis: A case report
Ramon Mariano Najarro II, Judith Valerie Akol
Chong Hua Hospital, Cebu City, Philippines

PP150 Going in from the back! Posterior approach to proximal humerus resection and endoprosthesis replacement
Prashant Narhari, Azuhairy Azid
Hospital Pulau Pinang, Georgetown, Malaysia

PP151 Reversible intra-operative cardiac arrest during intramedullary reaming of femoral metastasis: A case report
Thad Chetthanon¹, Chindanai Hongsaprabhas², Chris Charoenlap^3
1Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; ²Department of Orthopaedics, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand; ³Department of Orthopaedics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

PP152 Salvaging the limb salvage: Preoperative use of radiotherapy in recurrent osteosarcoma
Harzem Özger¹, Fulya Agaoglu², Bugra Alpan², Osman Emre Aycan³, Natig Valiyev³, Mustafa Sungur^2
1Istanbul Orthopedic Oncology Group, Istanbul, Turkey; ²Orthopaedics and Traumatology, Acibadem Mehmet Ali Aydinlar University Faculty of Medicine, Istanbul, Turkey; ³Orthopaedics and Traumatology, Acibadem Maslak Hospital, Istanbul, Turkey

PP153 Functional result of using custom-made bipolar to reconstruct for proximal femur lesions
Cheng-Han Lin, Karl Wu
Orthopedics/Far Eastern Memorial Hospital, New Taipei City, Taiwan

PP154 Similar local recurrence but better function with curettage versus resection for bone giant cell tumor and pathological fracture at presentation
Shinji Tsukamoto¹, Andreas Mavrogenis², Piergiuseppe Tanzi³, Giulio Leone⁴, Alberto Righi⁵, Manabu Akahane⁶, Akira Kido¹, Kanya Honoki¹, Yasuhito Tanaka¹, Davide Donati³, Costantino Errani^3
1Department of Orthopaedic Surgery, Nara Medical University, Kashihara-city, Japan; ²First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece; ³Department of Orthopaedic Oncology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy; ⁴Department of Orthopaedic Surgery, San Gerardo Hospital, Monza, Italy; ⁵Department of Pathology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy; ⁶Department of Public Health, Health Management and Policy, Nara Medical University, Kashihara-city, Japan

PP155 A comparison of limb salvage versus amputation for non-metastatic sarcomas using PROMIS outcomes
Benjamin Wilke¹, Anna Cooper², Mark Scarborough³, C. Parker Gibbs^3
1Mayo Clinic, Jacksonvile, United States; ²Loyola University, Chicago, United States; ³University of Florida, Gainesville, United States

PP156 Treating metastatic pathological fracture of the proximal humerus with the intramedullary nail
Cheng-Han Lee, Karl Wu
Orthopedic Department, Far-eastern Memorial Hospital, New Taipei City, Taiwan

PP157 Functional evaluation for patients with lower extremity sarcoma: application of the Chinese version of Musculoskeletal Tumor Society scoring system
Shoufeng Wang, Jin Xiong, Benlong Shi
Unit of Musculoskeletal Tumor, Nanjing Gulou Hospital, Nanjing University, Nanjing, China

PP158 Postoperative function and walking ability of hip transposition following resection of pelvic sarcoma
Toshiyuki Kunisada¹, Eiji Nakata¹, Joe Hasei¹, Masuo Senda², Toshifumi Ozaki^1
1Orthopaedic Surgery, Okayama University, Okayama, Japan; ²Rehabilitation, Okayama University, Okayama, Japan

PP159 Total femoral prosthesis replacement following resection of femoral malignant tumors
Hong Duan, Xiang Fang, Zeping Yu
West China Hospital, Sichuan University, Chengdu, China

PP160 The functional outcome of shoulder joint after tumor excision of shoulder girdle
Toshiharu Shirai^1,2, Ryu Terauchi¹, Shinji Tsuchida¹, Naoki Mizoshiri¹, Yuki Mori¹, Daichi Hayashi¹, Hiroyuki Tsuchiya², Toshikazu Kubo^1
1Department of Orthopaedics, Kyoto Prefectural University of Medicine, Kyoto, Japan; ²Department of Orthopaedic Surgery, Kanazawa University, Kanazawa, Japan

PP161 A systematic review of the functional outcome of endoprosthetic reconstruction for tumours around the knee in adults
Oluwaseyi K. Idowu¹, Mohamad Nasser¹, Michelle Maden¹, Adesegun T. Abudu^2
1Edge Hill University, Ormskirk, United Kingdom; ²Royal Orthopaedic Hospital, Birmingham, United Kingdom

PP162 Impact of orthopaedic management on skeletal metastasis; Early experience
Praveen Gupta
Bhagwan Mahaveer Cancer Hospital & Research Center, Jaipur, India

PP163 Rotationplasty in skeletally mature patients: A case series
Marjorie Sierra, Rafael Claudio, Richard Rotor, Jesus Adrian Duenas
Musculoskeletal Tumor Service, Philippine Orthopedic Center, Quezon, Philippines

PP164 Expandable endoprosthesis for bone sarcomas in children: Medium term functional outcomes
Surasak Prachapipat, Chandhanarat Chandhanayingyong, Apichat Asavamongkolkul, Saranatra Waikakul, Rapin Phimolsarnti
Department of Orthopaedic Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand

PP165 A time-based functional outcome evaluation following soft tissue sarcoma resections at a single Centre in Malaysia: Clinicians’ vs patients’ perspective
Azura Mansor, Venotha Madhialagan, Nor Faissal Yasin, Vivek Ajit Singh
University of Malaya Medical Centre, Kuala Lumpur, Malaysia

PP166 Autograft reconstruction after excision of primary bone tumors: Outcomes of patients seen at University of Santo Tomas Hospital
Martin Louie Bangcoy, Charles Abraham Villamin
University of Santo Tomas Hospital, Manila, Philippines

PP167 A case of myopericytoma in the quadriceps femoris muscle with gait disturbance without diagnosis and definitive treatment for 8 years
Yuichi Ichikawa, Jun Nishida, Takashi Koyama, Taro Nagai, Kengo Yamamoto
Dept. of Orthop. Surg., Tokyo Medical Univ., Tokyo, Japan

PP168 Comparative study of the standard intramedullary fixation of the bone metastasis associated or not with polimetilmetacrilate
Marcio Moura, Diego Sanches, Alvaro Ferreira Pinto, Sibele Sauzem Milano, Marcella Maria Villela
Federal Inversity of Parana, Curitiba, Brazil

PP169 Effects of exercise in patients with bone and soft tissue sarcomas: A literature study
Evanthia Mitsiokapa, Andreas Mavrogenis, Panayiotis Papagelopoulos
National and Kapodistrian University of Athens, Athens, Greece

PP170 Respiratory condition after partial sternal resection in two sarcoma cases treated with chest wall reconstruction of muscle flap
Toshinori Tsukanishi, Tsukasa Yonemoto, Hiroto Kamoda, Youko Hagiwara, Hideyuki Kinoshita, Takeshi Ishii
Chiba Cancer Center, Chiba, Japan

PP171 The functional outcome comparison of limb salvage surgery versus amputation for patients with high-grade osteosarcoma: A meta-analysis of the last 7-years studies
Sherly Desnita Savio, Maria Florencia Deslivia, Putu Astawa, I Gede Eka Wiratnaya
Orthopaedics and Traumatology Department, Faculty of Medicine Udayana University, Sanglah General Hospital, Denpasar, Indonesia

PP172 Ribbing disease in Oncólogos Del Occidente Oncology Clinic
Alvaro Bernal¹, Alberto Alvarado², Jose Martinez^3
1Orthopedic Oncology Service of Oncologos Del Occidente Oncology Clinic, Pereira, Colombia; ²Pathology Service of Oncologos del Occidente Oncology Clinic, Pereira, Colombia; ³Research Group of Oncologos del Occidente Oncology Clinic, Pereira, Colombia

PP173 Use of prolene mesh as reconstruction modality to prevent instability after distal fibula resection for tumor
Ashwinkumar Prajapati Prajapati, Ashish Gulia, Srinath Gupta, Vineet Kurisunkal, Hegde Prateek, Navaneeth Kamath, Prakash Nayak, Ajay Puri
Tata Memorial Hospital, Mumbai, India

PP174 Outcomes of short segment (less than 6cm) distal radius resections and wrist fusion with iliac crest bone grafting
Ashwinkumar Prajapati Prajapati, Gulia Ashish, Vineet Kurisunkal, Srinath Gupta, Prateek Hegde, Navaneeth Kamath, Prakash Nayak, Ajay Puri
Tata Memorial Hospital, Mumbai, India

PP175 Percutaneous cementoplasty on the management of painful osteolytic lesions of the acetabulum
Fábio Elói Pinto, Juliane Comunello, Suely Nakagawa, Tu Chung Wu
A.C.Camargo Cancer Center, São Pauo, Brazil

PP176 Provisional knee arthrodesis using the SIGN nail following proximal tibial resection can allow subsequent megaprosthetic limb salvage in low-resource settings
Mamer Rosario¹, Alvin Hernandez¹, Stephen Joseph Garcia², Paul Christian Bejosa¹, Pauline Del Rosario¹, Reynald Angelo Reyes¹, Erika Paulina Stefani See¹, Romer Ariel Santos¹, Misael Jonathan Ticman¹, Avelino Alomesen^3
1Department of Orthopaedics, East Avenue Medical Center, Quezon City, Philippines; ²Department of Medicine, East Avenue Medical Center, Quezon City, Philippines; ³Department of Pathology, East Avenue Medical Center, Quezon City, Philippines

PP177 The application of 3D-printing technology in pelvic bone tumor surgery
Jong Woong Park¹, Hyun Guy Kang¹, June Hyuk Kim¹, Han-Soo Kim^2
1National Cancer Center, Goyang, South Korea; ²Department of Orthopaedic Surgery, Seoul National University Hospital, Seoul, South Korea

PP178 Bone tumor resection guide using 3D-printing for limb salvage surgery
Jong Woong Park¹, Hyun Guy Kang¹, June Hyuk Kim¹, Han-Soo Kim^2
1National Cancer Center, Goyang, South Korea; ²Department of Orthopaedic Surgery, Seoul National University Hospital, Seoul, South Korea

PP179 Discussion about microwave ablation therapy
Qingyu Fan
Fourth Military Medical University, Xi'an, China

PP180 The secondary revision surgery with cemented custom-made tumor prostheses: A clinical case report
Shiquan Zhang, Wei You, Chuanxi Zheng, Hao Chen
Department of Orthopedic and Musculoskeletal Tumor, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University, Shenzhen, China

PP181 Impact and importance of international clinical collaboration on quality of orthopaedic cancer care
Pramod S. Chinder¹, Giovanni Beltrami⁴, Marco Manfrini³, Marco Colangeli³, Suraj Hindiskere^2
1HCG Hospital, Bangalore, Bangalore, India; ²The Yellow Ribbon, Karnataka, India; ³Istituto Ortopedico Rizzoli, Bologna, Italy; ⁴Azienda Ospedaliero Universitaria Careggi, Florence, Italy

PP182 Customized 3D endoprosthesis of the proximal tarsal phalanx for treatment of bone tumour: Finite element analysis
Surasak Prachapipat¹, Korakod Srikong², Natthapob Lakdee², Chedtha Puncreobutr², Boonrat Lohwongwatana³, Rapin Phimolsarnti¹, Chandhanarat Chandhanayingyong^1
1Departmet of Orthopaedic Surgery, Faculty of medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand; ²Meticuly Company Limited, Bangkok, Thailand; ³Department of Metallurgical Engineering, Faculty of Engineering, Chulalongkorn University, Bangkok, Thailand

PP183 Iliotibial tract flap for proximal femur tumor replacemented by megaprosthesis - Walking without claudication or supports
Marcio Moura¹, Olavo Pires de Camargo², Diego Sanches^1
1Federal University of Parana, Curitiba, Brazil; ²Sao Paulo University, Sao Paulo, Brazil

PP184 Nano-pillared titanium surfaces to prevent periprosthetic infections following limb salvage surgery
Richard Boyle¹, Dan Barker², Toby Brown², Krasi Vasilev³, Daniel Fernandes^3
1Royal Prince Alfred Hospital Sarcoma Unit, Camperdown, Australia; ²Corin Australia, Sydney, Australia; ³University of South Australia, Adelaide, Australia

PP185 Osseointegration potential of mesenchymal stem cells on porous 3D-printed Ti6Al4V scaffolds
George Vicatos, Esther Vernon (nee van Heerden)
Attri Orthopaedics Pty Ltd - University of Cape Town, Cape Town, South Africa

PP186 Ewing sarcoma 3D reconstruction. Right hand first metacarpal
Gaston Chiesa, Alejandro Ramaciotti, Pablo Sayago, Gabriel Martinez Lotti
COT-HPR, Rosario, Argentina

PP187 Preoperative embolization in hypervascular metastatic or primary tumors
Ji Won Lee¹, Yang-guk Chung¹, Seung Han Shin¹, Hae-Kyoo Lee², Yong-Koo Kang^3
1Department of Orthopedic Surgery, Seoul St. Mary's Hospital, College of Medicine, The CatholicUniversity of Korea, Seoul, South Korea; ²Department of radiology, Seoul St. Mary's Hospital, College of Medicine, The CatholicUniversity of Korea, Seoul, South Korea; ³Department of Orthopedic Surgery, Pyeongtaek St. Mary's Hospital, Pyeongtaek, South Korea

PP188 Bone remodelling of curetted benign tumours treated with elastic osteosynthesis, analysed by computed tomography
Edgard E Engel¹, Henrique M Natalin¹, Mariana DS Pontes¹, Tiago R Mascarenhas¹, Nelson F Gava¹, Marcello H Nogueira-Barbosa^2
1Orthopedics Department, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil; ²Imaging Division, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brasil

PP189 Applications of carbon fiber Intramedullary nails in orthopaedic oncology
Caleb Yeung, Nelson Merchan, Erik Newman, Joseph Schwab, Kevin Raskin, Santiago Lozano-Calderón
Massachusetts General Hospital, Boston, United States

PP190 High hip center tumor endoprosthesis reconstruction in periacetabular defects after internal hemipelvectomy
Harzem Özger¹, Bugra Alpan², Natig Valiyev³, Osman Emre Aycan^3
1Istanbul Orthopedic Oncology Group, Istanbul, Turkey; ²Orthopaedics and Traumatology, Acibadem Mehmet Ali Aydinlar University Faculty of Medicine, Istanbul, Turkey; ³Orthopaedics and Traumatology, Acibadem Maslak Hospital, Istanbul, Turkey

PP191 One-stage management with curettage and internal fixation for GCTB with pathologic fracture
Jin Xiong, Shoufeng Wang, Benlong Shi
Department of Orthopadic, Drum Tower Hospital, Nanjing University Medical School, Nanjing, China

PP192 Intercalary reconstruction using irradiated autologous bone graft with vascularized fibular graft as limb saving surgery for malignant tumors – The Philippine experience
Mary Rose Gonzales, Daniela Kristina Carolino, Richard Rotor, Edwin Joseph Guerzon, Henry Gerard Calleja, Jessica Anne Gandionco
St. Luke's Medical Center, Quezon City, Philippines

PP193 Customed segmental prostheses compared with bone graft to reconstruct the bone defect after resection of diaphyseal tumor
Zi Xiong Lei, Hao Miao Li, Ming Lu, Chang He Hou, Shao Hua Du, Wei Chen
The 3rd Affiliated Hospital of Southern Medical University, Guang Zhou, China

PP194 Articular degeneration after subchondral cementation of giant cell tumors at the knee
Cyrill Wechsler, Sandro Hodel, Christoph Laux, Christoph Stern, Andrea Rosskopf, Daniel Müller
University Hospital Balgrist, Zürich, Switzerland

PP195 Plate Assisted Bone Segment Transport (PABST) with motorized lengthening nails and locking plates - A technique to treat femoral and tibial bone defects
Daniel Eduardo Prince¹, John Herzenberg², Ulrik Kahler Olsen³, Tobias Nygaard³, Matthew P Gardner⁴, Upender Martin Singh³, Martin A. McNally⁵, Connor J. Green^6
1Memorial Sloan Kettering Cancer Center, New York, United States; ²Rubin Institute for Advanced Orthopedics , Baltimore, United States; ³Copenhagen Limb Lengthening and Bone Reconstruction Unit, Rigshospitalet , Copenhagen, Denmark; ⁴Springfield Clinic, Springfield, United States; ⁵Nuffield Orthopedic Centre, Oxford University Hospitals, Oxford, United Kingdom; ⁶Children’s University Hospital, Dublin, Ireland

PP196 Sarcomas occurring around the elbow – Clinicopathological features and outcomes
Jun Sugaya, Shintaro Iwata, Fumihiko Nakatani, Eisuke Kobayashi, Takeshi Komatsubara, Akira Kawai
National Cancer Center Hospital, Tokyo, Japan

PP197 Musculoskeletal sarcomas: Where vascular and orthopedic oncology surgery overlap
Andrea Angelini¹, Elisa Pagliarini¹, Michele Piazza², Andrea Spertino², Pietro Ruggieri^1
1Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy; ²Division of Vascular and Endovascular Surgery, University of Padova, Padova, Italy

PP198 Radiological and functional evaluation of bone union in frozen autograft and free vascularized fibular graft combination after intercalary resections of bone sarcoma in skeletally immature patients
Osman Emre Aycan¹, Bugra Alpan², Natig Valiyev¹, Harzem Ozger^3
1Orthopaedics and Traumatology, Acibadem Maslak Hospital Istanbul, Istanbul, Turkey; ²Orthopaedics and Traumatology, Mehmet Ali Aydinlar University Faculty of Medicine, Istanbul, Turkey; ³Istanbul Orthopaedic Oncology Group, Istanbul, Turkey

PP199 Biological reconstruction in osteosarcoma with epiphyseal involvement. Pushing up the limits
Harzem Özger¹, Bugra Alpan², Osman Emre Aycan³, Natig Valiyev^3
1Istanbul Orthopedic Oncology Group, Istanbul, Turkey; ²Orthopaedics and Traumatology, Acibadem Mehmet Ali Aydinlar University Faculty of Medicine, Istanbul, Turkey; ³Orthopaedics and Traumatology, Acibadem Maslak Hospital, Istanbul, Turkey

PP200 Giant-cell tumor of the first metacarpal bone in adolescent treated with denosumab followed by en-bloc resection and reconstruction with bone cement
Taweechok Wisanuyotin, Winai Sirichativapee
Department of Orthopaedics, Faculty of Medicine, Khon Kaen University, Thailand

PP201 3 epochs in the use of Implantcast growing endoprosthesis - Experience of the Warsaw Center - Institute of Mother & Child
Andrzej Szafranski, Bartosz Pachuta, Magdalena Rychlowska-Pruszynska, Iwona Malesza, Justyna Dusinska, Tomasz Walenta, Anna Raciborska
Department of Oncology and Surgical Oncology for Children and Youth, Institute of Mother & Child, Warsaw, Poland

PP202 Preservation of the ankle joint in the distal tibia malignances using trans-epiphyseal osteotomy and massive biologic reconstruction. Results and complications in 3 pediatric patients
Bart Kowalczyk, Krzysztof Miklaszewski, Anna Kuźnik-Buziewicz, Andrzej Pawelec, Paweł Maleta, Marcin Karlikowski
Orthopedic Department, University Children's Hospital of Krakow, Krakow, Poland

PP203 The outcome of tibial hemiprostheses replacement plus second stage revision as the treatment of the proximal tibial osteosarcoma in children
Yuan Li
Beijing Jishuitan Hospital, Beijing, China

PP204 Growth prediction value of 99mTc-MDP on epiphysis around the knee - An observational study from pediatric limb salvage for malignant bone tumors
Yuan Li¹, Tao Ji², Wei Guo², Qian Wang^1
1Department of Nuclear Medicine, Peking University People’s Hospital, Beijing, China; ²Musculoskeletal Tumor Center, Peking University People’s Hospital, Beijing, China

PP205 Two Free microvascular rotationplasty with nerve repair for rhabdomyosarcoma in a 18-month-old patient and in a osteosarcoma in a 8 year old patient
Francisco Baixauli, Alberto Perez-García, Marta Salom
Hospital Universitario Y Politecnico La Fe, Valencia, Spain

PP206 Customized Titanium printed metacarpal prosthesis for limb sparing surgery in an osteosarcoma child
Komkrich Wattanapaiboon¹, Yodsawee Pornmeechai¹, Worasun Taweewuthisub¹, Nattawut Sastravaha¹, Puwadon Weerapan², Arkaphat Kosiyatrakul², Suriya Luenam^2
1Queen Savang Vadhana Memorial Hospital, Chonburi, Thailand; ²Phramongkutklao Hospital, Bangkok, Thailand

PP207 Comparison of rotationplasty with non-invasive expandable endoprostheses: Single institutional study
Jennifer Thomson, Joseph Ippolito, Kathleen Beebe, Francis Patterson, Joseph Benevenia
Rutgers New Jersey Medical School, Newark, United States

PP208 Adult conversion of the repiphysis for skeletally immature patients with high grade sarcoma
Jennifer Thomson, Joseph Ippolito, Kathleen Beebe, Francis Patterson, Joseph Benevenia
Rutgers New Jersey Medical School, Newark, United States

PP209 Custom-made elbow joint reconstruction with free osteoperiosteal fibula and iliac crest flaps after tumor resection: report of two cases
Francesca Totti¹, Maurizio Scorianz¹, Elena Lucatelli², Mattia Brogi², Marco Innocenti², Giovanni Beltrami³, Domenico Campanacci¹, Rodolfo Capanna^4
1Orthopaedic Oncology and Reconstruction Surgery, Careggi University Hospital, Florence, Italy; ²Plastic and Reconstructive Microsurgery, Careggi University Hospital, Florence, Italy; ³Paediatric Orthopaedic Oncology, Careggi University Hospital, Florence, Italy; ⁴Orthopaedic Department, University of Pisa, Pisa, Italy

PP210 Epithelioid haemangioendothelioma of bone in a paediatric patient: A case report
Rodanthi Margariti¹, Vasileios Kontogeorgakos², Eftichios Papagrigorakis¹, Panagiotis Kolovos¹, Nikolaos Kotsakis¹, Dimitris Papadopoulos¹, Panagiotis Megremis¹, Christos Zambakides^1
1Orthopaedic Department, General Children's Hospital of Athens "P & A Kiriakou", Athens, Greece; ²Orthopaedic Department, National and Kapodistrian University of Athens, Athens, Greece

PP211 Surgical management of complications of expandable endoprostheses for skeletally immature patients with high grade sarcoma
Jennifer Thompson, Joseph Ippolito¹, Francis Patterson, Kathleen Beebe, Joseph Benevenia
¹Rutgers New Jersey Medical School, Newark, United States

PP212 Experience of using interlocking nail in pathologic proximal femur fracture
Karl Wu
Far Eastern Memorial Hospital, New Taipei City, Taiwan

PP213 A case of teratoma of the cauda equina with malignant transformation
Yoko Hagiwara¹, Ken Okazaki^2
1Chiba Cancer Center, Chiba, Japan; ²Tokyo Women's Medical Universty, Tokyo, Japan

PP214 Primary thoracic epidural malignant melanoma: A case report
Yasutaka Takagi¹, Hiroshi Yamada¹, Hidehumi Ebara¹, Hiroyuki Hayashi¹, Satoshi Kidani¹, Shunro Okamoto¹, Shintaro Terahata², Hiroyuki Tsuchiya^3
1Department of Orthopaedic Surgery, Tonami General Hospital, Tonami, Japan; ²Department of Pathology, Tonami General Hospital, Tonami, Japan; ³Department of Orthopaedic Surgery, Graduate School of Medicine, Kanazawa University, Kanazawa, Japan

PP215 Surgical management of lung cancer metastasis in the femur
Shoufeng Wang, Jin Xiong, Benlong Shi
Unit of Musculoskeletal Tumor, Nanjing Gulou Hospital, Nanjing University, Nanjing, China

PP216 Strategy for diagnosing of primary lesions in the metastatic bone and soft tissue tumors of unknown primary origin at the first visit
Taketsugu Fujibuchi, Joji Miyawaki, Teruki Kidani, Hiromasa Miura
Department of Bone and Joint Surgery, Ehime University Graduate School of Medicine, Toon, Japan

PP217 Skeletal metastasis in patients with prostate cancer
Tatsuya Takagi
Juntendo Univ., Tokyo, Japan

PP218 Intramedullary rod failure in metastatic breast cancer - Do triple negative cancer patients have more failures?
Ana Belzarena, Cecilia Belzarena, Odion Binitie, Douglas Letson, David Joyce
Sarcoma Department, University of South Florida, Moffitt Cancer Center, Tampa, United States

PP219 The heat transfer modelling for minimization of long bone metastasis lesion using the cement polymerization effect
Vania Oliveira¹, Elza Fonseca², Claudia Rua², Jorge Belinha², Paulo Piloto³, Renato Natal Jorge^4
1Oporto Hospital Center, ICBAS - Oporto University, Orthopaedics Department, Porto, Portugal; ²School of Engineering Polytechnic of Porto (ISEP), Mechanical Engineering Department, Porto, Portugal; ³Polytechnic of Institute of Bragança (IPB), Applied Mechanical Department, Bragança, Portugal; ⁴Faculty of Engineering of the University of Porto (FEUP), Mechanical Engineering Department, Porto, Portugal

PP220 Osteoblastic change in skeletal tumors decreases bone mineral density of cortical bone
Hajime Rikitake, Michiro Susa, Keisuke Horiuchi, Kazuhiro Chiba
Department of Orthopaedic Surgery, National Defense Medical College, Tokorozawa, Japan

PP221 Efficacy of multi-hole injection nails for intramedullary nailing with simultaneous bone cement injection in long bone metastases
Jong Woong Park¹, Hyun Guy Kang¹, June Hyuk Kim¹, Han-Soo Kim^2
1National Cancer Center, Goyang, South Korea; ²Department of Orthopaedic Surgery, Seoul National University Hospital, Seoul, South Korea

PP222 Treatment strategy for intramuscular metastases
Jun Nishida¹, Taro Nagai¹, Takashi Koyama¹, Yoshikuni Mimata², Takanori Hatanaka¹, Kengo Yamamoto^1
1Department of Orthopedic Surgery Tokyo Medical University, Tokyo, Japan; ²Department of Orthopaedic Surgery Iwate Medical University, Morioka, Japan

PP223 The clinical outcome of pulmonary metastectomy in musculoskeletal sarcoma patients in a single Centre: A retrospective cohort study
Nor Faissal Yasin, Thinesh Varan Subramaniam, Azura Mansur, Vivek Ajit Singh
National Orthopaedic Centre of Excellence for Research and Learning (NOCERAL), University of Malaya, Kuala Lumpur, Malaysia

PP224 Clinical manifestations of impending and pathological fractures indicated for conservative treatment in patients with metastatic tumors in the limb long bone
Kensaku Yamaga¹, Daichi Mukunoki¹, Mari Osaki¹, Koji Endo², Takeshi Minamizaki², Hideki Nagashima^1
1Department of Orthopedic Surgery, Faculty of Medicine, Tottori University, Yonago City, Japan; ²Department of Orthopedic Surgery, Yonago Medical Center, Yonago City, Japan

PP225 Withdrawn

PP226 Acetabular cage and cement reconstruction for acetabular metastatic disease
Scott Sommerville, Phillip Rowell, Martin Lowe, Ian Dickinson
The Wesley Hospital, Auchenflower, Australia

PP227 Electrochemotherapy: A reliable method to obtain pain control in bone metastases
Ugo Albertini¹, Michele Boffano¹, Andrea Conti^1,2, Elena Boux¹, Andrea Ferro¹, Stefano Marone¹, Laura Campanacci³, Raimondo Piana^1
1Oncologic Orthopaedic Surgery AOU Città della Salute e della Scienza Torino, Torino, Italy; ²Orthopaedic and Traumatology Clinic - University of Turin, Torino, Italy; ³Orthopaedic Oncology Dept - Rizzoli Orthopaedic Institute, Bologna, Italy

PP228 An algorithm proposal for the treatment of pathological fractures of the proximal femur in elderly people
Andrea Conti^1,2, Federico Bertolo^1,2, Michele Boffano¹, Nicola Ratto¹, Pietro Pellegrino¹, Stefano Marone¹, Andrea Ferro¹, Raimondo Piana^1
1Oncologic Orthopaedic Surgery AOU Città della Salute e della Scienza Torino, Torino, Italy; ²Orthopaedic and Traumatology Clinic - University of Turin, Torino, Italy

PP229 Efficacy analysis of separation surgery combined with precision radiotherapy for spinal metastases: A long-term follow-up study based on patients with spinal metastatic tumor in a single-center
Liu Xiaozhou, Zhou Guangxin, Shi Xin, Wu Sujia
Jinling Hospital, Nanjing, China

PP230 Withdrawn

PP231 Detection of pulmonary metastases using GFP transfected patient-derived osteosarcoma cells in patient-derived orthotopic xenograft (PDOX) model
Hiromichi Oshiro^1,2, Yasunori Tome¹, Tasuku Kiyuna¹, Hiroki Maehara¹, Hoffman Robert², Fuminori Kanaya^1
1Department of Orthopedic Surgery, Graduate School of Medicine, University of the Ryukyus, Nishihara-cho, Japan; ²Department of Surgery, University of California, San Diego, San Diego, United States

PP232 Evaluation of the surgical outcomes and postoperative complications for patients with femoral metastatic bone tumor
Hirotaka Yonezawa, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Yuta Taniguchi, Yoshihiro Araki, Sei Morinaga, Hiroyuki Tsuchiya
Department of Orthopaedic Surgery, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan

PP233 Limb salvage with a megaprosthesis in the elderly after failed prophylactic fixation in metastatic renal cell carcinoma
Nadine Williams, Alex Mierke, Omar Ramos, Lee Zuckerman
Loma Linda University Medical Center, Department of Orthopaedic Surgery, Loma Linda, United States

PP234 Long-term follow-up of Giant Cell Tumour (GCT) with pulmonary metastases
Sahran Yahaya, Wan Faisham Nu'man Wan Ismail, Norazman Mat Zin, Zulmi Wan
Universiti Sains Malaysia, Kota Bharu, Malaysia

PP235 Stabilisation of pathological humerus fractures using cement augmented plating: A case series
Alan Pickup, William Wilson, Helen Findlay, Ashish Mahendra,Sanjay Gupta
Glasgow Royal Infirmary, Glasgow, United Kingdom

PP236 C-reactive protein is a prognostic factor in metastatic bone disease
Patricio Alfaro¹, Giovanni Ciani², Lorenzo Ferra², Monica Cosentino², Barbara Bordini², Davide Maria Donati², Costantino Errani^2
1Hospital Traumatologico, Faculty of Medicine, Universidad de Concepcion, Concepcion, Chile; ² Department of Orthopaedic Oncology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy

PP237 Outcomes of extended curettage and cementation for metastatic bone tumors
Yang-guk Chung¹, Ji Won Lee¹, Seung Han Shin¹, Min Wook Joo², Yong-Koo Kang^3
1Department of Orthopedic Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea; ²Department of Orthopedic Surgery, St. Vincentl Hospital, College of Medicine, The Catholic University of Korea, Suwon, South Korea; ³Department of Orthopedic Surgery, Pyeongtaek St. Mary's Hospital, Pyeongtaek, South Korea

PP238 Late distant recurrences in treated cases of askin tumour - Two case reports
Vineet Kurisunkal, Ashish Gulia, Tushar Vohra, Ajay Puri
Tata Memorial Hospital, Mumbai, India

PP239 Hip pain associated with high risk of metastasis in elderly population
Nevzat Dabak², Sina Coskun¹, Ferhat Say², Hasan Göçer^2
1Samsun Training and Research Hospital, Samsun, Turkey, ²Ondokuz Mayis University Hospital Department of Orthopedics and Traumatology, Samsun, Turkey

PP240 The outcome of intramedullary nailing for metastatic bone tumors
Shunsuke Hamada, Nasa Fuzihara, Masahiro Yoshida, Satoshi Tsukushi
Aichi Cancer Center, Nagoya, Japan

PP241 Pulmonary metastasectomy in primary extremity osteosarcoma along with a brief review of literature
Chandra Kumar Krishnan, Vishnu Ramanujan, Arvind Krishnamurthy, Mayilvahanan Natarajan, Karthik T, Anand Raja
Cancer Institute (WIA), Chennai, India

PP242 Safety and efficacy of percutaneous vertebroplasty for treatment of osteoblastic spinal metastases pain relief
Xu Songfeng, Liu Ting, Yu Shengji, Zhao Zhenguo, Xu Libin, Zhang Xinxin
Department of Orthopedics, National Cancer Center / National Clinical Research Center for Cancer/ Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China

PP243 Use of Denosumab as neoadjuvant therapy followed by surgery in a series of cases of patients with giant cell tumor: Histological evaluation, articular preservation and pain
Eduardo Areas Toller, Sylvio Sargenttini, Ederson Kida, Vitor do Carmo, Ernesto Machin
Barretos Cancer Hospital, Barretos, Brazil

PP244 The efficacy and safety of apatinib in metastatic alveolar soft part sarcoma: A case series of six patients in one institution
Yitian Wang, Li Min, Yong Zhou, Yi Luo, Minxun Lu, Chongqi Tu, Fan Tang
Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, China

PP245 Epidermal growth factor receptor as a new target in the treatment of giant cell tumor of bone
Michal Mahdal¹, Jakub Neradil², Silvia Chovanova², Iva Zambo³, Lukas Pazourek¹, Tomas Tomas¹, Jakub Rapi^1
1Department of Orthopedic Surgery, St. Anne´s University Hospital/Faculty of Medicine Masaryk University, Brno, Czech Republic; ²Department of Experimental Biology, Faculty of Science Masaryk University, Brno, Czech Republic; ³Department of Pathology, St. Anne´s University Hospital/Faculty of Medicine Masaryk University, Brno, Czech Republic

PP246 Treatment for giant cell tumor of bone in our department for 25 years - What we learned using denosumab
Masami Hosaka¹, Munenori Watanuki², Kouu Hayashi², Shinichirou Yoshida², Toshihisa Yano², Masahito Hatori³, Osamu Dohi³, Shin Hitachi⁴, Mika Watanabe⁵, Eiji Itoi^2
1Dept. of Orthop. Surg., Miyagi Cancer Center, Natori, Japan; ²Dept. of Orthop. Surg., Tohoku University Graduate School of Medicine, Sendai, Japan; ³Dept. of Orthop. Surg., Tohoku Kosai Hospital, Sendai, Japan; ⁴Dept. of Pathol., Tohoku Univ. Hosp., Sendai, Japan; ⁵Dept. of Diag., Radiol., Tohoku Univ. Hosp., Sendai, Japan

PP247 Tricortical surgery for bone sarcomas: Experience of the Barretos Cancer Hospital
Eduardo Areas Toller, Sylvio Sargentini, Vitor Carmo
Barretos Cancer Hospital, Barretos, Brazil

PP248 Image-Guided total sacrectomy for chordoma - A case series
Hester Renel Palma, Judith Valerie Akol
Chong Hua Hospital, Cebu City, Philippines

PP249 Comparative analysis of the surgical treatment of giant cell tumor of pelvic bone assisted by computer navigation and traditional surgery
Qing Zhang, Lihui Xu, Haitao Zhao, Xiaohui Niu
Beijing Jst Hospital, Beijing, China

PP250 Is there a place for navigated surgical resection for osteoid osteomas?
Jose Ignacio Albergo, German Farfalli, Lucas Ritacco, Miguel Ayerza, Luis Aponte-Tinao
Hospital Italiano De Buenos Aires, Caba, Argentina

PP251 An ultrasound image-based surgical navigation using deep learning network for localization of intramedullary cystic bone lesions
Sanghyun Joung¹, Chul-woo Park¹, Ilhyung Park^1,2
1Medical Device and Robot Institute of Park, Kyungpook National University, Daegu, South Korea; ²Department of Orthopedic Surgery, Kyungpook National University Hospital, Daegu, South Korea

PP252 A computer assisted navigation technique to perform bone tumor resection without dedicated software
Carmine Zoccali¹, Jacopo Baldi¹, Nicola Salducca¹, Leonardo Favale¹, Roberto Biagini¹, Virginia Ferraresi^2
1Oncologica Orthopaedics, Irccs - Regina Elena National Cancer Institute, Rome, Italy; ²Medical Oncology 1, Irccs - Regina Elena National Cancer Institute, Rome, Italy

PP253 Navigated extremity sarcoma resection: Accuracy and reproducibility using a novel fluoroscopy-based registration technique for joint-sparing bone cuts
Ibrahim Alshaygy^1,2, Hun Lin², Jean Camille Mattei¹, Georges Basile¹, Jimmy Qiu², Michael Daly², Jason Townson², Harley Chan², David Jaffray^2,3,4, Jonathan C. Irish^2,5,6, Peter C. Ferguson^2,5,7, Jay S. Wunder^2,5,7
1University Musculoskeletal Oncology Unit, Mount Sinai Hospital, Toronto, Canada; ²Techna Institute, University Health Network, Toronto, Canada; ³Department of Radiation Physics, Princess Margaret Cancer Centre, Toronto, Canada; ⁴Ontario Cancer Institute, Princess Margaret Cancer Centre , Toronto, Canada; ⁵Department of Surgical Oncology, University Health Network, Toronto, Canada; ⁶Department of Otolaryngology-Head and Neck Surgery, University of Toronto, Toronto, Canada; ⁷Division of Orthopaedic Surgery, Department of Surgery, University of Toronto, Toronto, Canada

PP254 A daily diagnostic multidisciplinary meeting to reduce time to definitive diagnosis in the context of soft tissue and bone sarcoma
Laura Hartley, Michael Parry, Scott Evans, Jonathan Gregory, Mark Davies
The Royal Orthopaedic Hospital, Birmingham, United Kingdom

PP255 A case of elephantiasis nostra verrucosa: Approach to determining aetiology
Nor Hazla Mohamed Haflah, Syed Syafiq
Universiti Kebangsaan Malaysia, Cheras, Malaysia

PP256 Impact of perioperative allogeneic blood transfusion on prognosis in high-grade extremity sarcoma: A meta-analysis
Woo Young Jang, Jong Hoon Park
Korea University Anam Hospital, Seoul, South Korea

PP257 Sarcomas of the extremities: Comparing local recurrence after incisional and core needle biopsy
Alexander Klein¹, Annika Bilgeri¹, Volkmar Jansson², Hans Roland Dürr^1
1Orthopaedic Oncology; Department of Orthopaedics, Physical Medicine and Rehabilitation, University Hospital, LMU Munich, Munich, Germany; ²Department of Orthopaedics, Physical Medicine and Rehabilitation, University Hospital, LMU Munich, Munich, Germany

PP258 Langerhans cell histiocytosis of the spine in a child: A rare case and a diagnostic dilemma
Abigail Tud¹, Jose Bayani Aliling^2
1Department of Orthopedics, The Medical City, Pasig City, Philippines; ²Department of Orthopedics, The Medical City, Pasig City, Philippines

PP259 Post ISOLS 19th General Meeting 2017 in Kanazawa, Japan: How we have evolved
Srinath Doddarangappa¹, Pramod Chinder¹, Suraj Hindiskere¹, Tejashwini Anchan^2
1HCG Hospital, Bangalore, India; ²The Yellow Ribbon, Karnataka, India

PP260 Three cases of radiation-induced sarcoma
Daichi Mukunoki, Kensaku Yamaga, Mari Osaki, Hideki Nagashima
Tottori University, Yonago, Japan

PP261 Face to face appointment vs. telemedicine in first time appointment orthopedic oncology patients: a cost analysis
Luis Aponte-Tinao, Jose Albergo, German Farfalli, Fernando Plazzotta, Janine Sommer, Daniel Luna, Fernan González Bernaldo de Quirós
Hospital Italiano De Buenos Aires, Caba, Argentina

PP262 The comparison between conservative treatment and surgery of the ganglion cysts of wrist
Hanqiang Jin, Hongyi Zhu, Fang Yang, Ting Yuan
Shanghai Sixth People's Hospital, Shanghai, China

PP263 When should limb salvage surgery be considered during a medical mission?
Scott Nelson, Nadine Williams, Omar Ramos, Alex Mierke, Lee Zuckerman
Loma Linda University Medical Center, Department of Orthopaedic Surgery, Loma Linda, United States

PP264 Treatment outcome of the huge bone and soft tissue sarcoma
Kouji Kita, Kunihiro Asanuma, Tomohito Hagi, Tomoki Nakamura, Akihiro Sudo
Mie University, Tsu, Japan

PP265 Orthopaedic manifestations of melanoma and their management
Matthew DiCaprio, Mostafa Abousayed, Madhavi Kambam
Albany Medical Center, Albany, United States

PP266 Osteosarcoma sternum and clavicle; A case report
Badaruddin Sahito, Maratib Ali, Abdul Qadir, Mehtab Ahmed Pirwani, Nauman Hussain, Azam Kamboh
Dow University of Health Sciences, Civilhospital Karachi, Karachi, Pakistan

PP267 Challenges in imaging and histopathology
Salim Al-busaidi
Armed Forces Hospital (AFH), Al-Seeb, Oman

PP268 Bone lymphoma: A diagnostic challenge
Louis-Romée Le Nail, Rajesh Botshu, Vaiapuri Sumathi, Kim Tsoi, Michael Parry, Scott Evans, Lee Jeys
The Royal Orthopaedic Hospital, Birmingham, United Kingdom

PP269 Salvage of a lower limb with a distal femoral aseptic non-union and failure of the knee extensor mechanism, using an intramedullary segmental defect bridging knee arthrodesis system - A case presentation
Dimitrios Begkas, Alexandros Pastroudis,Stamatios-Theodoros Chatzopoulos, Evangelos Lymaxis, Panagiotis Panagopoulos, Ioannis Iliadis, Andreas Papageorgiou
Asclepieion Voulas General Hospital, 6th Orthopaedic Department, Athens, Greece

PP270 Outcomes of extraarticular resection and reconstruction as limb salvage option in musculoskeletal tumours involving joint – Systematic review and meta-analysis
Kishore Reddy^1,2,3, Rajashekar Danda², Pavan Murari², Abhilash Kumar^3
1American Oncology Institute, Hyderabad, India; ²Omni Hospital, Hyderabad, India; ³Citizens Hospital, Hyderabad, India

PP271 Pain around elbow: Not always tennis elbow!
Sina Coskun¹, Nevzat Dabak², Ferhat Say², Hasan Göçer^2
1Samsun Training and Research Hospital, Samsun, Turkey; ²Ondokuz Mayıs University Hospital Department of Orthopedics and Traumatology, Samsun, Turkey

PP272 Atypical osteoid osteoma cases presented with atypical location of the nidus
Sina Coskun¹, Nevzat Dabak², Hasan Göçer², Ferhat Say^2
1Samsun Training and Research Hospital, Samsun, Turkey; ²Ondokuz Mayis University Hospital Department of Orthopedics and Traumatology, Samsun, Turkey

PP273 Pathologic fracture of the proximal tibia in a 21-year-old secondary to Primary Non-Hodgkin lymphoma of bone managed with knee arthrodesis
Abigail Tud, Richard Rotor, Jesus Dueñas
Philippine Orthopedic Center, Quezon City, Philippines

PP274 Humeral involvement of multiple myeloma: Clinical characteristics and disease course
Ji-Won Lee, Seung-Han Shin, Yang-Guk Chung
Department of Orthopedic Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea

PP275 Treatment of a supraintercondylar multifragmented fracture of the distal, infected femur, with silver-coated tumor endomegaprosis
João Freitas, Ruben Fonseca, Alvaro Cuenhe, Paulo Tavares, José Casanova
Coimbra University Hospital, Coimbra, Portugal

PP276 Preliminary results of a novel knee arthrodesis system for the management of uncontrolled periprosthetic knee joint infection
Kadir Buyukdogan¹, Mehmet Ayvaz², Omur Caglar², Tolga Atay^3
1Koc University, Istanbul, Turkey; ²Hacettepe University, Ankara, Turkey; ³Suleyman Demirel University, Isparta, Turkey

PP277 The use of silver megaprostheses in the united states: Short-term outcomes in a multi-institutional review
Joseph Benevenia, Joseph Ippolito, Jennifer Thomson, Harry Temple, Richard Buch
Rutgers New Jersey Medical School, Newark, United States

PP278 Osteosarcoma arising in a case of osteofibrous dysplasia of tibia with classic adamantinoma: A case report
Sin Tak Benjamin Fong¹, Ka Lok Mak¹, WeiQuo Li¹, D.T.W. Yau², T.L. Lam², A.C.L. Chan², K.C. Lai³, M.K. Chan^3
1Department of Orthopaedics & Traumatology, Queen Elizabeth Hospital, Hong Kong, China; ²Pathology Department, Queen Elizabeth Hospital, Hong Kong, China; ³Department of Radiology & Imaging, Queen Elizabeth Hospital, Hong Kong, China

PP279 Condition of cellular factors of adaptive immunity in children with Nasopharengeal cancer
Nargiza Karimova, Djamila Polatova
Republican Specialized Scientific-practical Medical Centre of Oncology and Radiology, Ministry of Healthcare, Tashkent, Uzbekistan

PP280 Myoepithelioma of bone - A rare case
Peter Steadman^1,2, Geoff Strutton^1,2, Lisa Squires^1,2
1Australia New Zealand Sarcoma Association, Brisbane, Australia; ²Princess Alexandra Hospital, Brisbane, Australia

PP281 Prognostic significance of mitotic index using Pospho-Histone H3 immunostains in the diagnosis of giant cell tumor of bone
Manuel Ricardo Medellin Rincon¹, Vanessa Salinas¹, Mario Melo², Luis Carlos Gomez Mier¹, Camilo Soto Montoya^1
1Orthopaedics Department, Instituto Nacional De Cancerologia, Bogotá, Colombia; ²Pathology Department, Instituto Nacional De Cancerologia, Bogotá, Colombia

PP282 Osteochondroma of Hoffa’s Fat Pad. An uncommon clinical and radiological knee mass
Peter Steadman^1,2, Thomas Lloyd^1,2, Geoff Strutton^1,2
1Australia New Zealand Sarcoma Association, Brisbane, Australia; ²Princess Alexandra Hospital, Brisbane, Australia

PP283 Prognostic impact of CD44 expression in patients with myxofibrosarcoma
Hiroyuki Tsuchie¹, Makoto Emori², Naohisa Miyakoshi¹, Hiroyuki Nagasawa¹, Kyoji Okada³, Hiroshi Nanjyo¹, Yasutaka Murahashi², Emi Mizushima², Junya Shimizu², Toshihiko Yamashita², Yoichi Shimada^1
1Akita University Graduate School οf Medecine, Akita, Japan; ²Sapporo Medical University School of Medicine, Sapporo, Japan; ³Akita University Graduate School of Health Sciences, Akita, Japan

PP284 The prognostic significance of histopathological parameters for soft tissue sarcomas
Sahran Yahaya, Wan Haiery Wan Nor, Wan Yuhana WMS, Sharifah Emilia Tuan Sharif, Norazman Mat Zin, Wan Faisham Wan Ismail
Universiti Sains Malaysia, Kota Bharu, Malaysia

PP285 Pseudomyogenic haemangioendothelioma of bone: One institution five cases review
Eleonora Marini¹, Primo Andrea Daolio¹, Stefano Bastoni¹, Fabio Luca Giardina¹, Maria Serena Bartoli¹, Andrea Di Bernardo², Elisabetta Armiraglio², Antonina Parafioriti^2
1Orthopaedic Oncology Department, Milan, Italy; ²Pathology Department, Milan, Italy

PP286 Proximal humerus malignant pecoma. First ever case report
Prashant Narhari, Azuhairy Azid, Teik Junn Teoh, Charlene Su Yin Yeoh
Hospital Pulau Pinang, Georgetown, Malaysia

PP287 Pregnancy and delivery in female patients with pediatric, adolescent and young adult (AYA) pelvic sarcoma
Tsukasa Yonemoto¹, Hiroto Kamoda¹, Tshinori Tsukanishi¹, Hideyuki Kinoshita¹, Yoko Hagiwara¹, Hisao Osada², Takeshi Ishii^1
1Div. of Orthop. Surg., Chiba Cancer Center, Chiba, Japan; ²Dept. of Ob/Gyn, Chiba University Hospital, Chiba, Japan

PP288 A custom hemi-pelvic joint reconstruction with remaining of femoral head in peri-acetabular malignancies: a technical note of limb-salvaging surgery
Jingnan Shen, Junqiang Yin, Gang Huang, Changye Zou, Xianbiao Xie, Qinglin Jin
First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

PP289 The omentum as a biological barrier to prevent infection after pelvic tumor resection: a proof of concept
David Biau¹, Sébastien Gaujoux², Bertrand Dousset², Philippe Anract^1
1Orthopedics, Paris Descartes, AP-HP, Paris, France; ²General Surgery, Paris Descartes, AP-HP, Paris, France

PP290 CHondrosarcoma of the Pelvis: surgical management options and outcomes of 41 cases
Zeping Yu, Xiang Fang, Hong Duan
West China Hospital, Sichuan University, Chengdu, China

PP291 Anatomical-Compartmental System to stratify wound complications after internal hemipelvectomy
Koichi Ogura, Patrick J. Boland, Nicola Fabrri, John H. Healey
Memorial Sloan Kettering Cancer Center, New York, United States

PP292 What nature taught and how technology helped- 5year story of a pelvic tumour
Srinath Doddarangappa¹, Pramod Chinder¹, Suraj Hindiskere¹, Vidisha Murathane^2
1HCG Hospital, Bangalore, India, ²The Yellow Ribbon, Karnataka, India

PP293 Chondrosarcoma pelvis, beyond the boundaries
Badaruddin Sahito, Maratib Ali, Dileep Kumar, Nauman Hussain Rajput
Department of orthopaedic surgery unit 1, Ruth K M Pfau Civil Hospital, Dow University of Health Sciences, Karachi, Pakistan

PP294 The Baby bump and the malignant lump: A case report of a pregnant patient with pelvic sarcoma
Daniela Kristina Carolino, Mary Rose Gonzales, Richard Rotor
Institute of Orthopedics and Sports Medicine, St. Luke's Medical Center, Quezon City, Philippines

PP295 Surgical treatment for pelvic Ewing sarcoma involving the acetabulum: What is a safe and functional reconstruction combined with modern multi-disciplinary treatments?
Tomohiro Fujiwara, Yusuke Tsuda, Jonathan Stevenson, Michael Parry, Robert Grimer, Lee Jeys
The Royal Orthopaedic Hospital, Birmingham, United Kingdom

PP296 Adamantinoma of pelvis: A rare entity at an unusual location with a difficult diagnosis
Jagandeep Virk¹, Manish Pruthi¹, Bharat Rekhi², Sunil Pasricha^1
1Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, New Delhi, India; ²Tata Memorial Hospital (TMH), Mumbai, India

PP297 Intraoperative computer-assisted navigation (Intellijoint HIP®) system for periacetabular reconstruction in pelvic tumor surgery
Koichi Ogura, Tomohiro Fujiwara, John H. Healey, Nicola Fabbri
Memorial Sloan Kettering Cancer Center, New York, United States

PP298 Vertical abdominoinguinal approach (Extended Battle incision): A novel approach for pelvic resections
Walid Ebeid¹, Usama Said Imam^2
1Orthopaedic Department, Cairo University, Cairo, Egypt; ²General Surgery Department, Beni Sweif University, Beni Sweif, Egypt

PP299 Vascularized and recycled hybrid bone graft to restore hip function after resection of periacetabular bone tumor
Koichiro Ihara, Takatomo Mine, Hiroyuki Kawamura, Ryutaro Kuriyama, Yasuhiro tmonaga
NHO Kanmon Medical Center, Shimonoseki, Japan

PP300 Οne stage intramedullary total femoral replacement for post-irradiation proximal femur non-union and ipsilateral knee osteonecrosis
Christos Vottis¹, Katsuhiro Hayashi³, George Georgopoulos², Leonidas Dimopoulos², Vasilis Aggelis², Panayiotis Papagelopoulos^2
1Evgenideio Hospital, Orthopedic Department, University of Athens, Athens, Greece; ²Attikon University Hospital, 1st Orthopedic Department, University of Athens, Athens, Greece; ³Department of Orthopedic Surgery, Kanazawa University Kanazawa, Japan

PP301 Titanium silk vs polymeric tube. As soft tissue reconstruction option in patients with hip replacement after tumor resection
Ilkin Mikailov, Petr Grigorev
Russian Research Institute of Traumatology and Orthopedics Named After R.R.Vreden, St-Peterburg, Russian Federation

PP302 Cement spacer formed in a patient-specific mould based on a three-dimensional bone model. A case report
G. Ulrich Exner¹, Charles E. Dumont¹, Jonas Walker², Philipp Fuernstahl^2
1Orthopaedie Zentrum Zuerich, Zurich, Switzerland; ²CARD Computer Assisted Research & Development Group, University Hospital Balgrist, University of Zurich, Zurich, Switzerland

PP303 Knee arthroplasty after failure of osteoarticular tibia allografts in adults. Problems, complications, solutions
G. Ulrich Exner¹, Pascal A. Schai², Tobias C. Bühler³, Theodore I. Malinin^4
1Orthopaedie Zentrum Zuerich, Zurich, Switzerland; ²KSL Wolhusen, Wolhusen, Switzerland; ³KS Baden, Baden, Switzerland; ⁴University of Miami Tissue Bank, Miami, United States

PP304 A novel 3D-printed tumor prosthesis for reconstruction of proximal humerus and shoulder
Yidan Zhang, Yi Yang, Haijie Liang, Tao Ji, Ran Wei, Xiaodong Tang, Dasen Li, Zhiye Du, Jie Zang, Rongli Yang, Wei Guo
Musculoskeletal Tumor Center, Peking University People's Hospital, Beijing, China

PP305 Revision rates for megaprostheses: A updated review of the literature and meta-analysis
Jean-Camille Mattei¹, Arnaud Felden², Philippe Anract², David Biau^2
1Hôpitaux De Marseille, Aix Marseille Université, Marseille, France; ²Hôpitaux de Parais, Paris Descartes Université, Paris, France

PP306 Proximal femoral replacement with bipolar heads - What is the risk of secondary conversion to THA?
Christoph Theil¹, Tom Schmidt-Braekling¹, Georg Gosheger¹, Hannah Thoennissen¹, Jendrik Hardes¹, Dimosthenis Andreou¹, Burkhard Möllenbeck¹, Marcel-Philipp Henrichs², Ralf Dieckmann^1
1Universitätsklinikum Münster, Deparment of Orthopaedics and Tumour Orthopaedics, Münster, Germany; ²Deparment of Orthopaedics, Paracelsus Hospital, Osnabrück, Germany

PP307 Reconstruction of osseus defects in the upper limb by 3D printed protheses following the resection of primary malignant bone tumors of the long bones - presentation of two cases with a two-year-follow-up
Thomas Ackmann, Julian Röder, Sebastian Klingebiel, Kristian Schneider, Georg Gosheger, Dimosthenis Andreou
Department of General Orthopedics and Tumor Orthopedics, University Hospital Münster, Münster, Germany

PP308 Custom mega prosthesis in metachronous osteosarcoma
Mayil Vahanan Natarajan¹, MI Mohamed Sameer², KP Manimaran^3
1M. N. Orthopaedic Hospital, Chennai, India; ²Sri Ramachandra Medical college, Chennai, India; ³Madras Medical College, Chennai, India

PP309 Medium-term follow-up results of reconstruction related complications after En bloc resection for thoracolumbar tumors
Ming Lu, Haomiao Li, Zixiong Lei, Shuangwu Dai, Changhe Hou, Wei Chen, Shaohua Du
Department of Orthopedic, The Third Affiliated Hospital of Southern Medical University, Guangzhou, China

PP310 Pelvic resection and reconstruction using revision hip and knee prostheses composite in a patient with a metastatic pelvic tumor: A case report
Ervin Chino Tayag¹, Raymond Barba¹, Charles Abraham Villamin¹, Martin Louie Bangcoy^1
1University of Santo Tomas Hospital, Manila City, Philippines

PP311 Mega-prosthesis in bone tumors, AKUH experience
Masood Umer, Eraj Khurshid, Javeria Saeed
Aga Khan University Hospital, Karachi, Pakistan

PP312 Is acetabular replacement an option in proximal femur EndoProsthetic replacement?
Flavia Alberghina^1,2, Gennaro Parisi^1,2, Michele Boffano¹, Ugo Albertini¹, Nicola Ratto¹, Pietro Pellegrino¹, Raimondo Piana^1
1Oncologic Orthopaedic Surgery AOU Città della Salute e della Scienza Torino, Torino, Italy; ²Orthopaedic and Traumatology Clinic - University of Turin, Torino, Italy

PP313 Clinical experience of intercalary endoprosthetic reconstruction for malignant mid-diaphyseal bone tumors of femur and tibia
Takaaki Tanaka, Yoshinori Imura, Toru Wakamatsu, Hironari Tamiya, Norifumi Naka
Osaka International Cancer Institute, Osaka, Japan

PP314 Reconstruction of the humerus using the Comprehensive Segmental Revision System in patients suffering from metastatic bone disease. A retrospective study of a consecutive cohort of patients
Claus Lindkær Jensen, Michala S. Sørensen, Michael M. Petersen
Department of Orthopaedics, Musculoskeletal Tumor Section, Copenhagen, Denmark

PP315 Revisions for lower limb mega-prosthesis aseptic loosening failure: Short-stem cemented GMRS modular reconstructive prosthesis may serve as a good option
Hairong Xu, Yuan Li, Xiaohui Niu
Department of Orthopaedic Oncology Surgery, Beijing Ji Shui Tan Hospital, Beijing, China

PP316 Hip arthroplasty in metastatic bone disease of the hip, experience at Hospital Metropolitano, Quito – Ecuador
Ricardo Ramón, Esteban Holguin, Carlos Ballesteros, Edgar Barros
Hospital Metropolitano, Quito, Ecuador

PP317 Elective polyethylene change for peri-knee endoprostheses. Is it a good idea?:A series of five patients and retrieval study
May Fong Chan, Lester Wai Mon Chan, Matthew Hern Wang Cheng
Tan Tock Seng Hospital, Singapore

PP318 The custom distal tibial endoprosthesis – From design lab to the operating theatre
Suraya Zainul-Abidin¹, George Vicatos², Henry Soeharno¹, Mann Hong Tan^1
1Singapore General Hospital, Singapore; ²University of Cape Town, Cape Town, South Africa

PP319 Telescoping stem: Rare complication of a total elbow megaprosthesis
Raymond Yau, Kenneth Wai-Yip Ho, Ying-Lee Lam
Department of Orthopaedics & Traumatology, Queen Mary Hospital, Hong Kong

PP320 Three dimentional printed customized endoprosthesis for massive defect of pelvic pubic ramus: prosthesis design and surgical techniques
Yuqi Zhang, Jie Wang, Minxun Lu, Fan Tang, Li Min, Yong Zhou, Yi Luo, Chongqi Tu
Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, China

PP321 Uncemented three-dimensional printed prosthetic reconstruction for giant cell tumor of distal tibia
Minxun Lu, Yuqi Zhang, Jie Wang, Li Min, Yi Luo, Yong Zhou, Fan Tang, Chongqi Tu
West China Hospital, Sichuan University, Chengdu, China

PP322 Clinical and radiographical outcomes of proximal femur cemented stems in tumor endoprostheses
Anas Nooh, Abdulrahman Alaseem, Marc-Antoine Ricard, Krista Goulding, Robert Turcotte
Department of Orthopedic Surgery, McGill University Health Centre, Montreal, Canada

PP323 Silver-surface-modified megaprostheses: Do medium-term results (two to eight years follow-up) confirm initial promises for postoperative infection control?
Guido Scoccianti¹, Francesco Muratori¹, Filippo Frenos¹, Xhulio Prifti¹, Giovanni Beltrami¹, Rodolfo Capanna², Domenico Andrea Campanacci^1
1Department of Orthopaedic Oncology, Careggi University Hospital, Firenze, Italy; ²Department of Orthopaedics, Pisa University, Pisa, Italy

PP324 The role of additive manufacturing in surgical planning and in patient-specific implants
George Vicatos
Attri Orthopaedics Pty Ltd, Cape Town, South Africa

PP325 Sarcomatous transformation in Hereditary multiple osteochondromatosis
Salvador Ausina, Laura Izquierdo, Antonio López, Concepción Crespo,María José Mayol, Jorge Salvador
San Juan University Hospital, Alicante, Spain

PP326 3-D-printed titanium scapula prosthesis in the treatment of osteosarcoma secondary to hereditary multiple exostosis: A case report
André Mathias Baptista¹, Andre Ferrari de Franca Camargo¹, Rafael Aron Schmerling², Luciano Ruiz Torres¹, Geanete Pozzan², Whinsgton Pereira^1
1University of Sao Paulo, Sao Paulo, Brazil; ²Hospital Beneficencia Portuguesa de Sao Paulo, Sao Paulo, Brazil

PP327 3D-printed custom-made prosthetic reconstructions: analysis of 41 cases in two referral Centers
Andrea Angelini¹, Daniel Kotrych², Giulia Trovarelli¹, Andrej Szafrański², Antonio Berizzi¹, Andrzej Bohatyrewicz², Pietro Ruggieri^1
1Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy; ²Department of Orthopedics, Traumatology and Orthopedic Oncology, Pomeranian Medical University, Szczecin, Poland

PP328 Proximal humerus resection and reconstruction with Modular Reverse Total Shoulder Prosthesis: long-term results on 30 patients treated by a single surgeon
Giulia Trovarelli, Alessandro Cappellari, Elisa Pala, Andrea Angelini, Antonio Berizzi, Pietro Ruggieri
Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

PP329 Post radiation pathologic femur fractures in soft tissue sarcomas: Is endoprosthetic reconstruction is a good option?
Ibrahim Alshaygy, Georges Basile, Jean Camille Mattei, Anthony Griffin, Jay Wunder, Peter Ferguson
Mount Sinai Hosptial, Toronto, Canada

PP330 10 year review of over 700 cases using a traditional then altered antibiotic protocol for tumour megaprosthesis
Richard Boyle, Daniel Franks, Paul Stalley, Angie Pinto, Wiliiam McNamara
RPAH, Sydney University, Newtown, Australia

PP331 Total elbow replacement using “Cost Effective Indigenous Implant”
Navaneeth Kamath, Ashish Gulia, Ajay Puri, Prakash Nayak, Prateek Hegde, Srinath Gupta, Vineet Kurisunkal
Tata Memorial Hospital, Mumbai, India

PP332 Tumor reaction due to orthopedic implants after total hip arthroplasty - Diagnostic between tumor, challenge for early and adequate treatment
Marcio Moura, Amanda De Oliveira, Guilherme Do Fonno, Mateus Veiga Caires
Federal University of Parana, Curitiba, Brazil

PP333 Partial two-stage revision for infected tumor prostheses: Is stem retention a reasonable option?
Jean-Camille Mattei¹, Mansour Abolghasemian², Julia Visgaus³, Anthony Griffin², Jay Wunder², Peter Ferguson^2
1Hôpitaux De Marseille - Aix Marseille Université, Marseille, France; ²Mount Sinai Hospital, Toronto, Canada; ³Duke University, Durham, United States

PP334 Evaluation of the impact of radiation on the healing of femural fractures and the effectiveness of centrifugated human amniotic fluid on the healing of irradiated bone tissue
Cláudio Gonçalves, Luiz Teixeira, Ivana Duval, Márcia Michelin, Márcio Pereira, Pedro Machado
Federal University of Minas Gerais, Belo Horizonte, Brazil

PP335 Early outcomes of soft tissue sarcoma treated with preoperative hypofractionated radiation and immediate resection
Lukas Nystrom, Nathan Mesko, Brian Rubin, Joshua Lawrenz, Shireen Parsai, Chirag Shah, Jacob Scott
Cleveland Clinic, Cleveland, United States

PP336 Adjuvant brachytherapy with immidiate flap reconstructions in recurrent extremity soft tissue sarcoma: A series of 10 cases
Vishnu Ramanujan, Vishwa Madesh, Anand Raja, Mayilvahanan Natrajan
Cancer Institute (WIA), Adyar, Chennai, India

PP337 Mid-to long-term clinical outcomes of hemicorticalresection and reconstruction using liquid nitrogen-treated tumor-bearing bone in osteosarcoma patients
Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Yu Aoki, Yuta Taniguchi, Hirotaka Yonezawa, Yoshihiro Araki, Sei Morinaga, Hiroyuki Tsuchiya
Kanazawa University, Kanazawa, Japan

PP338 Does reimplantation of sterlised tumor bone benefit survival in diaphyseal osteosarcoma?
Ajay Puri, Prakash Nayak, Ashish Gulia, Siddharth Laskar
Tata Memorial Hospital, Mumbai, India

PP339 Frozen autograft treated by liquid nitrogen with vascularized fibula for the reconstruction after excision of malignant tumors
Yoshikazu Tanzawa¹, Akira Kawai², Eisuke Kobayashi², Takuya Watanabe¹, Masato Sato¹, Masahiko Watanabe¹, Hiroyuki Tsuchiya^3
1Tokai University, Isehara, Japan; ²Division of Musculoskeletal Oncology, National Cancer Center Hospital, Tokyo, Japan; ³Department of Orthopaedic Surgery, Kanazawa University, Kanazawa, Japan

PP340 Our early experience with liquid nitrogen sterilization for osteosarcoma of extremities: 28 cases from India
Suraj Hindiskere, Pramod Chinder, Srinath Doddarangappa
HCG Hospital, Bangalore, India

PP341 Histological study on liquid nitrogen-treated tumor-bearing bone of the proximal femur retrieved after implantation
Yoshikazu Tanzawa¹, Akira Kawai², Fumihiko Nakatani², Masahiko Watanabe¹, Hiroyuki Tsuchiya^3
1Tokai University, Isehara, Japan; ²Division of Musculoskeletal Oncology, National Cancer Center Hospital, Tokyo, Japan; ³Department of Orthopaedic Surgery, Kanazawa University, Takara-machi, Kanazawa, Japan

PP342 Patellar cryo-free technique with recycled frozen autograft reconstruction may be a better alternative to preserve the extensor mechanism for malignant proximal tibial bone tumors
Chao Ming Chen^1,2,3, Po Kuei Wu^1,2,3, Jir You Wang^1,2,3, Wei Ming Chen^1,2,3
1Therapeutic and Research Center of Musculoskeletal Oncology, Department of Orthopedic Surgery and Traumatology,Taipei Veterans General Hospital, Taipei City, Taiwan; ²Institute of Clinical Medicine, School of Medicine, National Yang-Ming University, Taipei City, Taiwan; ³Department of Orthopedics, School of Medicine, National Yang-Ming University, Taipei City, Taiwan

PP343 Limb salvage with extracorporeal irradiation and graft prosthetic composite for osteosarcoma of proximal tibia: A case report
Srimanth Bindiganavile, Vadhiraj Manjunath
Manipal Hospitals, Bengaluru, India

PP344 A comparison of frozen and irradiated autograft reconstructions for limb salvage
Edgard Engel¹, Yuri O Machado¹, Lídia M Prada¹, Mateus A Hernandes², Nelson F Gava^1
1Orthopedics Department, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brasil; ²Image Division, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brasil

PP345 High grade pediatric sarcomas - Nitrogen technique treatment
Eduardo Sadao Yonamine, Bruna Buscharino, Karen Voltan, Anderson Rodrigues Santos, Aires Leite Jr, Mario Cavalcanti, Murilo Alexandre, Elio Consentino, Jose Donato Prospero
Santa Casa Medical School of Sao Paulo, Sao Paulo, Brazil

PP346 Oncologic, Surgical and functional outcomes following limb-sparing surgery with vascular reconstruction in patients with extremity musculoskeletal tumors: A retrospective single center case series
Abraham Saad, Surasak Prachapipat, Apichat Asavamongkolkul, Saranatra Waikakul, Rapin Phimolsarnti, Chandhanarat Chandhannayingyong
Department of Orthopaedic Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand

PP347 Patella giant cell tumor – A benign entity with intricate treatment approach: Case report
Mohamed Hafizudin Abdullah Sani, Nor Hazla Mohamed Haflah
UKMMC, Cheras, Malaysia

PP348 Propeller flaps in management of irradiated sarcoma defects
Eldon Mah
St. Vincent's Hospital Melbourne, Fitzroy, Australia

PP349 Meniscus-meniscal ligament complex: A new and accessible material suitable for reconstructing the soft tissue defect after resection of malignant bone tumors around knee
Junqiang Yin, Yiwei Fu, Changye Zou, Gang Huang, Jingnan Shen
Department of Musculoskeletal Oncology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

PP350 Pork or beef? A two-arm comparison of synthetic membranes in reconstructions of peri-articular resections
Saminathan Suresh Nathan
Limb Salvage and Revision Arthroplasty Surgery Pte Ltd, Singapore

PP351 Soft-tissue reconstruction in malignant myoepithelioma of the anteromedial proximal leg
Joey Kueisheng Lin, Cesar Cipriano Dimayuga
The Medical City, Pasig City, Philippines

PP352 A histological positive margin after surgery is correlated with high local re-recurrence rate in patients with recurrent myxofibrosarcoma running title: Outcomes of recurrent myxofibrosarcoma
Kazutaka Kikuta¹, Robert Nakayama², Akihiko Yoshida⁴, Akira Kawai³, Masaya Nakamura², Morio Matsumoto^2
1Division of Musculoskeletal oncology and Orthopaedic Surgery/ Tochigi Cancer Center, Tochigi, Japan; ²Department of Orthopaedic Surgery/ Keio University School of Medicine, Tokyo, Japan; ³Division of Musculoskeletal Oncology/ National Cancer Center Hospital, Tokyo, Japan; ⁴Division of Pathology and Clinical Laboratory/ National Cancer Center, Tokyo, Japan

PP353 Clinical course of soft tissue sarcomas presenting as malignant wounds
Manabu Hoshi, Naoto Oebisu, Tadashi Iwai, Akiyoshi Shimatani, Naoki Takada, Hiroaki Nakkamura
Department of Orthopedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan

PP354 Management of malignant peripheral nerve sheath tumors: Prognostic factors and survival in a series of patients treated at a single institution
Naoto Oebisu, Manabu Hoshi, Tadashi iwai, Akiyoshi Shimatani, Naoki Takada, Hiroaki Nakamura
Osaka City University Graduate School of Medicine, Osaka, Japan

PP355 Efficacy of radio-hyperthermo-chemotherapy as salvage therapy for recurrent or residual malignant soft tissue tumors
Hisaki Aiba¹, Satoshi Yamada¹, Takanobu Otsuka², Hideki Murakami^1
1Nagoya City University, Nagoya, Japan; ²Tokai Gakuen University, Nagoya, Japan

PP356 Clinicopathological features of superficial epithelioid sarcomas
Naofumi Asano¹, Akihiko Yoshida², Koichi Ogura³, Eisuke Kobayashi³, Masaya Nakamura¹, Morio Matsumoto¹, Robert Nakayama¹, Toru Hiruma⁴, Takeshi Ishii⁵, Akira Kawai^3
1Department of Orhopaedic Surgery, Keio University School of Medicine, Tokyo, Japan; ²Department of Pathology, National Cancer Center Hospital, Tokyo, Japan; ³Department of Musculoskeletal Oncology, National Cancer Center Hospital, Tokyo, Japan; ⁴Division of Musculoskeletal Tumor Surgery, Kanagawa Cancer Center, Yokohama, Japan; ⁵Division of Orthopaedic Surgery, Chiba Cancer Center, Chiba, Japan

PP357 A retrospective study of prognostic factors, treatment modalities and outcome of soft tissue sarcoma of extremities: Universiti Kebangsaan Malaysia Medical Centre (UKMMC) Experience
Nor Hazla Mohamed Haflah, Soon Kang Law, Fuad Ismail
Universiti Kebangsaan Malaysia, Cheras, Malaysia

PP358 The expression and clinical significance of PD-1/PD-L1 in extraskeletal osteosarcoma
Yongzhong Wei, Jingjing Xu, Juming Li
Department of Orthopedic Surgery, The First Affiliated Hospital With Nanjing Medical University, Nanjing, China

PP359 Experience of interstitial permanent i(125) brachytherapy for extremity soft tissue sarcomas
Hong Duan, Xiang Fang
West China Hospital, Sichuan University, Chengdu, China

PP360 Is resection of soft tissue sarcomas other than tumor centers leading to an uncorrectable mistake? Review of 492 single center operated soft tissue sarcoma patients
Andac Celasun Alsina¹, Federico Sacchetti², Ozgur Mert Bakan¹, Dundar Sabah^1
1Ege University, Izmir, Turkey; ²Pisa University, Pisa, Italy

PP361 Sarcopenia affects incidence of surgical wound complications in localized soft tissue sarcoma patients but not outcome
Roberto Vélez¹, Matias Vicente¹, Matias De Albert², Manuel Perez-Dominguez^1
1Orthopaedic Oncology, Hospital Vall D´ Hebron, Barcelona, Spain; ²Radiology, Hospital Vall D´ Hebron, Barcelona, Spain

PP362 Application of circulating tumor cell detection in soft tissue sarcoma
Juming Li, Yumin Huang
Jiangsu Province Hospital, Nanjing, China

PP363 Muscle strength preservation in patients who underwent soft tissue sarcoma resection in the thigh is dissociated from psychological parameters of the quality of life
Liza Ranzani, Carlos Hanasilo, Leandro Auletta, Mauricio Etchebehere
Department of Orthopaedics and Traumatology, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil

PP364 Surgical results and risk factors for complications and limb function in patients with soft tissue sarcomas of the thigh
Sei Morinaga, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Yuta Taniguchi, Hirotaka Yonezawa, Yoshihiro Araki, Hiroyuki Tsuchiya
Department of Orthopaedic Surgery, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan

PP365 Evaluation of local recurrence risk of unplanned primary excision of soft tissue tumor without additional wide excision at an early stage
Ryu Terauchi, Shinji Tsuchida, Naoki Mizoshiri, Yuki Mori, Daichi Hayashi, Toshiharu Shirai
Department of Orthopaedics, Kyoto Prefectural University of Medicine, Kyoto, Japan

PP366 A case report of basal cell carcinosarcoma in left lower leg
Toshihisa Yano¹, Munenori Watanuki¹, Masami Hosaka², Kouu Hayashi¹, Shinichiro Yoshida¹, Mika Watanabe³, Shin Hitachi⁴, Eiji Itoi^1
1Dept. of Orthop. Surg., Tohoku Univ. Graduate School of Medicine, Sendai, Japan; ²Dept. of Orthop. Surg., Miyagi Cancer Center, Natori, Japan; ³Dept. of Pathology, Tohoku Univ. Hosp., Sendai, Japan; ⁴Dept. of Diagnostic Radiology, Tohoku Univ. Hosp., Sendai, Japan

PP367 Analysis of treatment outcomes and factors affecting long-term survival in patients with epithelioid sarcoma: A long-term follow-up study of patients with epithelioid sarcoma by multicenter
Liu Xiaozhou¹, Wu Sujia¹, Wei Yongzhong², Wang Shoufeng^3
1Department of Orthopedics, Jinling Hospital, Nanjing, China; ²Department of Orthopedics, Jiangsu Province hospital, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China; ³Department of Orthopedics, Nanjing Drum tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China

PP368 Neoadjuvant radiotherapy for soft tissue sarcoma in China: A preliminary result
Huang Zhen
Beijing Jishuitan Hospital, Beijing, China

PP369 Impact of adjuvant therapy using acridine orange in patients with soft tissue sarcoma treated with marginal resection: A comparative study
Hiroyuki Tsuchie¹, Makoto Emori², Naohisa Miyakoshi¹, Hiroyuki Nagasawa¹, Kyoji Okada³, Yasutaka Murahashi², Emi Mizushima², Junya Shimizu², Toshihiko yamashita², Yoichi Shimada^1
1Akita University Graduate School of Medecine, Akita, Japan; ²Sapporo Medical University School of Medicine, Sapporo, Japan; ³Akita University Graduate School of Health Sciences, Akita, Japan

PP370 Douple primary sarcoma
Jaeyoung Lee¹, Seung-Han Shin^2
1Department of Orthopedic Surgery, Bucheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Bucheon, South Korea; ²Department of Orthopedic Surgery, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea

PP371 Epidemiology, incidence, and survival of rhabdomyosarcoma subtypes: SEER and ICES Database Analysis
Kamil Amer¹, Jennifer Thomson¹, Dominick Congiusta¹, Andrew Dobitsch¹, Anthony Bozzo², Kathleen Beebe^1
1Rutgers New Jersey Medical School, Montclair, United States; ²McMaster University, Hamilton, Canada

PP372 Predictive factors of synovial sarcoma
Philipp Theodor Funovics, Klemens Vertesich, Markus Schreiner, Heiko Schmid-Stino, Gerhard Hobusch, Joannis Panotopoulos, Reinhard Windhager
Medical University of Vienna Department of Orthopaedics and Trauma Surgery, Vienna, Austria

PP373 Oncological outcomes of extraskeletal osteosarcoma: Our experience
Prateek Hegde, Vineet Kurisunkal, Navaneeth Kamath, Ashwinkumar Prajapati, Srinath Gupta, Prakash Nayak, Ashish Gulia, Ajay Puri, Avadhoot Dixit
Tata Memorial Hospital, Mumbai, India

PP374 Soft tissue pleomorphic sarcoma: Diagnostic approach and treatment
Giakoumis Diakoumis, Ioannis Papakostas, Spyros Valvis, Serafeim Sarafopoulos, Sofia Dara, Theodoros Kormas<
Agios Savvas Oncological Hospital, Athens, Greece

PP375 The effects of neoadjuvant radiation therapy on local recurrence in treating myxofibrosarcomas
Ashley Aratani, Taylor Reif, Mark Scarborough, Parker Gibbs, Chung Chan, Dianne Torrence, Andre Spiguel
University of Florida, Gainesville, United States

PP376 Unplanned excisions of soft tissue sarcomas of the upper extremity
Vasileios Kontogeorgakos, Annelies Van Beeck, Rodanthi Margariti, Stauros Goumenos, Olga Savvidou, Andreas Mavrogenis, Panagiotis Papagelopoulos
Attikon University Hopsital, National and Kapodistrian University of Athens, Athens, Greece

PP377 A rare case of melanotyc schwannoma involving the sacrum
Levent Berkem¹, Mehmet Aydogan², Sefa Giray Batibay³, Ayse Bahar Ceyran⁴, Korhan Özkan^5
1Department Of Orthopaedics And Traumatology, Goztepe Training and Research Hospital, Istanbul, Turkey; ²Free Physician, Istanbul, Turkey; ³Department of Orthopaedics and Traumatology, Derince Training and Research Hospital, Kocaeli, Turkey; ⁴Department of Pathology, School of Medicine, Bilim University, Istanbul, Turkey; ⁵Department of Orthopaedics and Traumatology, Medical School, Medeniyet University, Istanbul, Turkey

PP378 Early clinical results of the second generation total en bloc spondylectomy for spinal tumor: Experience from a developing country
Permsak Paholpak¹, Taweechok Wisanuyotin¹, Winai Sirichativapee¹, Yuichi Kasai¹, Hideki Murakami^2
1Department of Orthopedics, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand; ²Department of Orthopedics, Faculty of Medicine, Nagoya City University, Nagoya, Japan

PP379 Surgical treatment of bone tumors affecting the sacroiliac joint
Roger Rojas Sayol¹, Laura Noguera Alonso², Ana Peiró Ibañez¹, Laura Trullols Tarragó¹, Pau Machado Granados¹, Gemma Vilà Canet², Ana Belen Pérez Romera², Juan José Velazquez Fragoso², Isidro Gracia Alegria^1
1Orthopaedic Oncology Unit, Orthopaedic Department, Hospital De La Santa Creu I Sant Pau, Barcelona, Spain; ²Spine Surgery Unit, Orthopaedic Department, Hospital De La Santa Creu I Sant Pau, Barcelona, Spain

PP380 Evaluation of functional outcome following early and late surgical intervention for spine metastases: Single institutional experience of 132 patients
Amrithlal Mascarenhas, Pramod Chinder, Suraj Hindiskere, Srinath Doddarangappa
HCG Hospital, Bangalore, India

PP381 Percutaneous spinal endoscopy treatment for recurrent sacral metastases
Tenghui Zeng, Xinjian Yang, Shiquan Zhang
Department of Spine Surgery, The 1st Affiliated Hospital of Shenzhen University, China

PP382 An analysis for reliability of spinal instability neoplastic score of spinal metastasis patients in residents training program
Phutsapong Srisawat, Kritsadakorn Waithayayothin, Sutipat PairojBoriboon, Puwadon Veerapan, Thipachart Punyaratabandhu
Department of Orthopedics, Phramongkutklao Hospital & College of Medicine, Bangkok, Thailand

PP383 Intraoperative Tranexamic acid reduces early drainage after the resection of primary sacral tumor
Changhe Hou, Haomiao Li, Zixiong Lei, Ming Lu, Shuangwu Dai, Shaohua Du, Wei Chen
Department of Muscular Skeletal Oncology, Third Affliated Hospital, Southern Medical University, Guangzhou, China

PP384 Complications after partial, total or extended sacrectomy in a serie of cases
Mauro Costa Morais Tavares Junior¹, Douglas Kenji Narazaki², William Gemio Jacobsen Teixeira², Cesar Salge Gilhardi², Alexandre Fogaça Cristante¹, Tarcisio Eloy Pessoa de Barros Filho^1
1Department of Orthopedics and Traumatology, University of Sao Paulo, Sao Paulo, Brazil; ²Department of Spine Surgery, Cancer Institute of Sao Paulo, Sao Paulo, Brazil

PP385 Experience of successful surgical treatment for lumbar giant cell tumour
Hirotaka Koyanagi, Toshitaka Yoshii, Takashi Hirai, Shingo Sato, Atsushi Okawa
Tokyo Medical and Dental University Hospital, Tokyo, Japan

PP386 Perioperative nursing care of en-bloc resection for malignant peripheral nerve shealthtumor of lumbar
Han Yan, Haomiao Li, Changhe Hou, Shuangwu Dai, Ming Lu, Wei Chen
Southern Medical University, Guangzhou, China

PP387 Biological scaffold in the age of 3D printing: Extracorporeal radiation and re-implantation after total sacrectomy
Manit Gundavda, Manish Agarwal, Rajeev Reddy
P.D. Hinduja Hospital And MRC, Mumbai, India

PP388 Evaluation of lateral extent of the reactive layer around subcutaneous soft tissue sarcomas by ultrasonography
Munenori Watanuki¹, Masami Hosaka², Kou Hayashi¹, Sinichirou Toshida¹, Toshihisa Yano¹, Eiji Itoi^1
1Dept. of Orthop Surg, Tohoku University Hospital, Sendai, Japan; ²Dept. of Orthop Surg, Miyagi Cancer Center, Natori, Japan